79 results
to investigate the analgesic effect of high frequency 10 Hz rTMS on experimental pain measured through quantitative sensory testing (QST) in healthy subjects.
To determine the direct effects of morning light intensity on postprandial glucose and lipid metabolism and metabolic gene expression in adipose tissue.
To test the hypothesis that metabolic inflexibility in pre-diabetic subjects and diabetic patients is due to a reduced capacity to form acetylcarnitines: We aim to investigate whether glucose intolerant subjects have a lower capacity to form acetyl-…
Primary Objective: To study the change on performance on executive function and memory function (as measured on Neurocart), after an active challenge with methylphenidate (monoaminergic) and galantamine (cholinergic), compared to placebo, in…
Primary Objective: To investigate whether exercise (Diabetes Bootcamp) induces a change in intestinal faecal microbiota (rise of butyrate-producing intestinal microbiota) related to improved glycaemic control (peripheral and hepatic insulin…
In this study, we aim to investigate the difference in the anabolic postprandial bile acid response between an enteral and parenteral mixed meal test (MMT) in healthy lean men. This study is important because it may give a better understanding of…
The primary objectives are to investigate whether L-carnitine infusion may rescue lipid-induced insulin resistance and whether L-carnitine infusion is improving metabolic flexibility in the state of lipid-induced insulin resistance. Furthermore,…
To identify which component of hemodialysis is primarily involved in the reduction in myocardial blood flow.
The primary objective of this study is to assess if cannabinoids modulate sweet taste intensity and liking.
To investigate whether increased aldosterone levels in obese individuals lead to impairment of microvascular function through reduction of NO-availability, and to establish the role of microvasculaire dysfunction in the pathogenesis of salt-…
To examine the effect of remote ischemic preconditioning on exercise-induced cTn elevations and indices of cardiac function.
To investigate the effect of elevated levels of endogenous lactate on brain lactate accumulation and on counterregulatory responses to, symptomatic awareness of and cognitive function during hypoglycemia in patients with T1DM with and without…
1. To assess whether acute TRPV1 activation by capsaicin or ENaC down regulation by flavonoids modulate osmoregulation in healthy subjects2. To assess whether capsaicin and flavonoids affect blood pressure
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
The primary objective of the biomarker study is to validate existing biomarkers for protein from dairy, meat, and grain/ legumes, and to identify new potential biomarkers for these types of protein in urine. Secondary objectives are 1) to establish…
To determine the effect of sensory signals on satiety and food preferences.
The current protocol aims to test the effects of intervals between subsequent startle measurements on the sensitivity of FPS to alcohol.
To study the effects of 2 weeks of supplementation with high gelling-high viscous fibre on energy intake in healthy subjects compared to a placebo with similar texture.
For a possible (better) treatment of FOG a better understanding of the brainmechanism behind this phenomenon is needed. Previous studies showed some brain areas that are possibly involved in FOG.The aim of this study is to see whether we can induce…
Not applicable.