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Trigeminovascular effects of propranolol in migraine treatment

To determine the mechanism of action of propranolol in the prophylactic treatment of migraine.

Food-effect study of weekly administration of (bi-)daily Oral Docetaxel (ModraDoc006) in combination with ritonavir

To determine the effect of a high-fat meal on the exposure to docetaxel given as ModraDoc006 tablets in combination with ritonavir in patients with cancer.