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The effects of mastication and sweetness on cephalic phase responses

Primary aim: To determine the effects of oro-sensory exposure stimulation through mastication duration and sweetness intensity on the endocrine and metabolic cephalic phase responses.Secundary aim: To determine whether the magnitude of cephalic…

A double blind, randomized, placebo controlled, cross-over study to validate the predictive power of the demarcation formula for Lybrido and Lybridos efficacy in women with female sexual interest/arousal disorder, in the domestic situation.

Primary Objective• To validate the existing demarcation formula (consisting of psychometric and biological markers) which predicts the sensitivity to Lybrido or Lybridos in women with female sexual interest/arousal disorder (FSIAD with or without…

Flavour nutrient learning of vegetables

To understand more of the learning principles of vegetable consumption in young children (2-4 years). The aim of this study is to investigate the effect of flavour nutrient learning on vegetable preference and intake. Primary Objective: To…

*Why does the number of bites affects satiation? A possible role for cognition**

The objective of this study to investigate the role of attention on the effect of NB on ad libitum intake.

The effectiveness of mindfulness based cognitive therapy (MBCT) in adults with chronic, therapy resistant depression in a mental healthcare setting?

The aim of this study is to examine whether MBCT is also effective in patients with chronic, treatment-resistant depression in a mental healthcare setting.

Cognitive behavioral therapy for Misophonia, RCT

To evaluate the effect of the CBT groep treatment for misophonia.

A Placebo- and Active-Controlled Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Subjects With Major Depressive Disorder

Primary ObjectiveTo evaluate the effect of a single 84-mg dose of intranasal esketamine compared to placebo, on next day driving performance and repeated administration of 84 mg intranasal esketamine on same-day driving performance as assessed by…

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the CNS Effects of Single and Multiple Doses of CST-101, CST-103, and CST-109 in Healthy Subjects and Patients with Parkinson*s Disease

The primary objectives of this study are:Part A 1. To characterize the effects of single doses of beta-adrenoceptor (β-AR) agonists CST-101, CST-103 and β AR partial agonist CST-109 on the functional domains of the central nervous system (CNS), as…

Effect of food additive E171 (titanium dioxide) on the development of colorectal cancer, an early biomarkers research.

In this intervention study, the primary aim is to evaluate the influence of E171 exposure on the gene expression profile in rectal biopsies. In addition, inflammatory markers such as ROS in the rectal epithelium will be measured as secondary outcome…