39 results
This research will have as aim to look at progression or decrease of vascular calcification in dialysis population with use of different phosphate binders. There is a possibility that differect phosphate binders bind vitamin K in a different way in…
The objective of this feasibility study is compare the smart AFO + standardized shoes to subjects* own AFO + own shoes. Subjects* experiences with the orthotic devices will be evaluated and points for improvement will be asked. Subjects* performance…
The first objective of this study is to evaluate the effect of standard HD with different dialysate calcium concentrations as well as HD combined with citrate-acid dialysate on the clearance of CPPs and second the effect of these different solutions…
Primary Objective- To investigate the ability of TMS-EEG measures to detect effects on cortical excitability of valproic acid, levetiracetam and lorazepam in healthy subjects- To investigate the ability of TMS-EMG measures to detect effects on…
The purpose of the study is to investigate how quickly and to what extent BAY 1834845 is absorbed and eliminated from the body (this is called pharmacokinetics). In both study parts it will also be investigated to what extent BAY 1834845 is…
The main objective of our study is to explore whether LTH and FMD are correlated. Main secondary objectives are to investigate whether the LTH response is largely NO-mediated and whether drinking beetroot juice acutely improves both FMD and LTH.
To assess the effects of a 4-week high protein diet on body composition in obese children. Secondary outcomes are whole-body protein turnover, gluconeogenesis, energy expenditure, markers of the metabolic syndrome, appetite sensations,…
Primary objective of this pilot study is to evaluate the in vivo effect of a B2-agonists in CF patients with residual CFTR function, using dosages which are clinically used in patients with asthma. Secondary objective is to evaluate the difference…
The aim of this study is to examine whether MBCT is also effective in patients with chronic, treatment-resistant depression in a mental healthcare setting.
The primary objective of this study is to determine the effects of aliskiren, as compared to ramipril, on renal hemodynamics in overweight/obese and hypertensive patients.
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The primary objective is to quantify and compare the effect of added arabinose to sucrose containing liquid and solid food products on glycaemic response and sucrose hydrolysis by sucrase and glucose absorption in healthy humans.The secundary…
Primary Objective: Getting insight in the effect of the use of the Genupoint patellar strap on knee joint proprioception in subjects with patellar tendinopathy.Secondary Objective(s): Getting insight in the effect of the use of the Genupoint…
Primary objective:The purpose of this study is to evaluate the short term effect of a patellar strap on symptoms and sports participation in children with Osgood-Schlatter disease.Secondary objective: The second objective of this study is to…
To evaluate the effect of the CBT groep treatment for misophonia.
Primary ObjectiveTo evaluate the effect of a single 84-mg dose of intranasal esketamine compared to placebo, on next day driving performance and repeated administration of 84 mg intranasal esketamine on same-day driving performance as assessed by…
- To evaluate the single-dose PK and pivotal bioequivalence of 3 compounds darunavir (DRV) 675 mg, FTC 200 mg, and tenofovir alafenamide (TAF) 10 mg in the presence of cobicistat (COBI)150 mg when administered as an fixed-dose combination (FDC) (D/C…
Primary objective: Our key objective is to determine if a cannabinoid manipulation is more effective than a glucocorticoid manipulation to facilitate fear memory extinction retention in an experimental model of exposure therapy in healthy…
The aim of this research is to find out more about the speed at which different types of proteins are digested and absorbed into the blood. This is important because differences in the rate of digestion and absorption can affect the nutritional…
To determine the efficacy of silver enhanced gloves in decreasing burden of Raynaud*s phenomenon in patients with systemic sclerosis.