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In vivo induction of heme oxygenase-1 (HO-1) in the metabolic syndrome (MetS).
Influence of heme arginate (Normosang) infusion on heme oxygenase-1 activity, endothelial dysfunction, insulin resistance and adipose tissue inflammation related to the metabolic syndrome

Our main objective is to determine the effect of HO-1 induction by heme arginate infusion on insulin resistance and endothelial dysfunction related to MetS. Secondary objectives are to determine the effect on adipose tissue, adiponectin plasma level…

Probiotics in atherosclerosis: a pilot study

The objective of the study is to see whether oral administration of probiotics can modulate certain immunological markers which are associated with accelarated atherosclerosis in patients with ANCA associated vasculitis.

The effect of ischemic preconditioning in patients with cerebral small vessel disease

To explore the effect of single versus repeated preconditioning on circulating blood factors (i.e. metabolomics analysis) as a likely mechanism in patients with cSVD. Secondly, we explore whether the effects of single versus repeated preconditioning…