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A randomized clinical trial investigating LanreotIde For output reduction in patients with high-output Enterocutaneous fistula or enterostomie

To assess the impact of treatment with Lanreotide versus current standard of treatment on output reduction in patients with high output enterocutaneous fistula or high-output stoma.

Endoluminal fundoplication with the Esophyx*-device versus proton-pump-inhibition in treatment of Gastro-esophageal reflux disease (GERD).

The purpose of this prospective randomized controlled trial is to demonstrate that the EsophyX-TIF procedure will be more effective than PPI therapy as a short and long-term treatment of GERD.

A Randomized, Double-blind, Placebo-controlled, Multicenter Efficacy Study of the Gelstix* Device to treat Chronic Discogenic Low Back

The primary objective of this study is to quantify the reduction in lumbar pain in a GelStix* treatment group compared with a control group receiving a saline solution injection as placebo.The secondary objectives are to assess: 1. the impact of…