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Rate Adaptive Atrial Pacing in Heart Failure Patients with Chronotropic Incompetence

Primary Objective The primary objective of this pilot study is to assess the ability of MV sensor driven rate adaptive atrial stimulation to restore the quality of life in CI heart failure patients.Secondary Objective(s)The secondary objectives of…

Health effects due to inhalation of ultrafine particles in healthy volunteers. Multiple short-term exposures to UFP near Schiphol Airport.
A cross-over study

We hypothesize that the toxic potency of UFP from air traffic is comparable to road traffic after inhalation by healthy humans. Therefore, we aim to:* Identify acute effects of short-term inhalation of ultrafine particles right next to Amsterdam…