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POLYP DETECTION WITH THE PEERSCOPE SYSTEM*: A RANDOMIZED TANDEM COLONOSCOPY STUDY

To compare the additional diagnostic yield obtained by using the PeerScope System* extended view vs. the diagnostic yield obtained by the Standard view colonoscopy.In addition, time measurements including time to cecum, time for withdrawal and…

Gastro-intestinal permeability and intense physical activity (GRINTA)

Primary Objective is to compare the effect of different exercise protocols on intestinal permeability and on plasma levels of glutamine and glutamine-derived amino acids, in healthy young men. A Secondary Objective is to assess the effect of…

Methods to examine intestinal permeability under different conditions.

The effect of a high-fat breakfast on intestinal permeability will be examined in lean and obese men to see if a fat load can induce increased intestinal permeability and it is a feasible challenge test to investigate effects of foods / ingredients…

Assessment of patients with PPI-refractory GORD: reflux monitoring with or without proton pump inhibitor?

Objective: To compare the yield of Symptom Association Probability with two approaches to investigate patients with PPI-resistant symptoms: 24-hour pH monitoring off PPI and 24-hour impedance monitoring on PPI.

Colonoscopic surveillance using narrow-band imaging in patients with hyperplastic polyposis syndrome (HPS)

The aims of this study are to assess the additional value of NBI in comparison to white-light endoscopy (WLE) for the detection and classification of HPs, SAs, MPs and adenomas in patients with HPS.

The use of narrow band imaging versus conventional colonoscopy for the detection of dysplasia and cancer in patients with longstanding ulcerative colitis. A randomized cross-over study

1) to compare NBI and standard White Light Endoscopy (WLE) for the detection of neoplasia during colonoscopic surveillance of patients with longstanding UC2) To determine the accuracy of Kudo*s classification in distinguishing neoplastic from non…

InTerlaboratory Evaluation of a GastroIntestinal Activity Ergometertest in Non-intense Trained PersOns

The primary objective is to evaluate the lab transferability of the exercise model as used in the GRINTA! study. This will be achieved by comparing the effect of exercise on biomarkers in blood, urine and saliva in two different laboratories. These…

Wide Area Transepithelial sample Esophageal Biopsy combined with Computer assisted 3-Dimensial Tissue Analysis (WATS) for the detection of High Grade Esophageal Dysplasia and Adenocarcinoma: A multicenter prospective, randomized, tandem study

To evaluate the utility of the WATS system, as a potential substitute for the random sampling method that is currently recommended as an adjunct to targeted biopsy

InTerlaboratory Evaluation of a GastroIntestinal Activity ErgoMeterTest in Non-intense Trained PersOns

Primary Objective: To determine effects of less exercise,30 min 70% Wmax, on intestinal function and immune response in blood, urine and saliva.Secondary Objective: Interlaboratory evaluation of the ergometertest performed in Groningen and Utrecht…