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A pharmacokinetic study of Docetaxel and Prednisone in men with metastatic castration-resistant or hormone-sensitive prostate cancer.

In this study we therefore investigate the influence of prednisone on docetaxel exposure in metastatic prostate cancer patients.

Improving bio-availability of the expensive oral oncolytic drug abiraterone by food intake

Primary objective:To determine the equivalent dose of abiraterone when taken with a continental breakfast compared to 1000 mg in fasted stateSecondary objective:To evaluate the preference of the patients: intake of abiraterone with or without food