14 results
Our primary objective is to investigate whether oxytocin administration can affect empathy and emotion recognition in healthy and antisocial adolescents. We expect that oxytocin will enhance empathy and emotion recognition in both healthy and…
To investigate acute effects of a single 40 mg dose hydrocortisone, compared with placebo, on stress and various aspects of attention and other cognitive processing of emotionally relevant stimuli in healthy anxious young females. The main question…
The closer examination of acute effects of a single administration cortisol. compared to placebo, on different aspects of attention and other cognitive processing of emotionally relevant stimuli in healthy young men. The central question is what…
To study whether the administration of oxytocin leads to stronger empathic responses on 3 different empathy-related tasks compared to a placebo.
Study 1:- Determine whether loss aversion behaviour (i.e. increased sensitivity to losses compared to gains) is modulated by dopamine levels using a pharmacological challenge- Assess whether this effect is accompanied by the modulation of brain…
- To investigate whether olanzapine influences the (psychomimetic) effects of THC, in particular on the Positive and Negative Syndrome Scale (PANSS) - To further explore the pharmacologic basis of the THC model - To investigate the effects of…
• Identify regional specificity of dopaminergic drug effects, i.e. the distinct behavioural roles of dopamine in the striatum and dopamine in the prefrontal cortex.• Identify receptor specificity of dopaminergic drug effects, i.e. the distinct…
To further study effects of a single administration of cortisol, compared to placebo, on different aspects of attention and other cognitive processing of emotionally relevant information in healthy young men. This should provide new information on…
The aim of this project is to test the hypothesis that MDD patients with disturbances in anger/aggression regulation have more serotonin disturbances, as a trait marker for relapse, than MDD patients without disturbances in anger/aggression…
-Identify the neural correlates of enhanced formation of emotional memory, and parse the role of adrenal stress hormones in this process.-Identify the neural correlates of enhanced consolidation of emotional memory and parse the role of adrenal…
We aim to develop a proxy-model of baseline dopamine based on machine learning methods which would provide us with behavioural predictors of the effects of dopaminergic drugs on brain and cognition that maximally generalize to new participants.
The primary objective of this study is to unravel the effects of dopamine D2 receptor stimulation on gating of working memory, reinforcement learning, and reward-based motivation, and their associated physiological changes (measured with fMRI and…
To demonstrate that combined phMRI/phMRS can characterize the dose-dependent neurometabolic response to S-ketamine.