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Think different. A study into the feasibility and the effectiveness of an online Cognitive Bias Modification training on an app for adolescents with an obsessive compulsive disorder (OCD)

This study concerns research into the applicability and effectiveness of CBM-I training through an app on the mobile phone. The research is done in adolescents (12-18 years) treated at the Bascule clinic for OCD. The training will take place during…

Degrading traumatic memories, a functional MRI study in PTSD

To extend our understanding of brain mechanisms involved in intrusive memory degrading by eye movement during recall of traumatic memories in the treatment of PTSD.Brain areas involved in visual imagery are well-documented, and comprise the primary…

Magnitude of contextual startle potentiation as a function of inter startle interval: A pilot study and a cross-over alcohol design

The current protocol aims to test the effects of intervals between subsequent startle measurements on the sensitivity of FPS to alcohol.

Critical investigation of the mechanisms at work in EMDR: A pilot study

The aim is to test whether EM in EMDR contributes to a reduction in dysfunctional beliefs about recalling the traumatic memory. A sample of Dutch veterans diagnosed with PTSD will be tested. During three EMDR treatment sessions we will measure…

Critical investigation of the mechanisms at work in EMDR

The aim is to test whether EM in EMDR contributes to a reduction in dysfunctional beliefs about recalling the traumatic memory. A sample of Dutch veterans diagnosed with PTSD will be tested. During three EMDR treatment sessions we will measure…

An explorative study to establish the panicogenic effects of a single versus double vital capacity 35% carbon dioxide inhalation challenge

To investigate the difference in response between single and double vital capacity 35% CO2/65% O2 in terms of the occurrence of PA*s in healthy subjects as measured with the Panic Symptoms List-IV (PSL-IV) and VAS subjective anxiety and fear.

Dual tasking in the treatment of posttraumatic stress disorder (PTSD): does the emotional valence of the distracting task matter?

To verify whether the emotional valence of the distracting task will affect the effects of the dual tasking procedure in a help seeking PTSS population.

Methodological trial to investigate the dose-response relationship, test-retest reliability and tolerance to repeated exposure of the 35% carbon dioxide experimental panic challenge in CO2-sensitive healthy volunteers

To investigate the dose-response relationship, test-retest reliability and tolerance to repeated exposure of the 35% carbon dioxide experimental panic challenge in CO2-sensitive healthy volunteers as measured with the PSL-IV total Score, VAS Fear,…