27 results
This study has been transitioned to CTIS with ID 2023-510257-42-01 check the CTIS register for the current data. Sodium-glucose cotransporter 2 (SGLT2) inhibitors lead to a lowering of blood pressure and confer cardiovascular and renal protection in…
Metabolic effects of ketohexokinase inhibition in individuals with non-alcoholic fatty liver disease
Primary objective: determining the effect of the ketohexokinase inhibitor, PF-06835919, on hepatic insulin sensitivity in individuals with non-alcoholic fatty liver disease.Secondary objective: determining the effect of the ketohexokinase inhibitor…
In this randomised, double-blind, placebo-controlled cross-over single centre study we propose to study the effect of duodenal infusion of single E. Hallii treatment of 10 ml 10E9/ml in 10% glycerol or 10ml 10 % glycerol (administered via duodenal…
The study investigates whether the glycemic response to standardized snacks differs within subjects between different times of the day. The study concerns a pilot for a future larger study of more complex aspects of the nutritional and physical…
Evaluate the effect of the adjustable rocker, the self-adjusting insole, and a combination of both on in-shoe plantar peak pressures in patients with diabetes related neuropathy.
The main objective of the study is to determine the albuminuria lowering effect of the GLP1-RA exenetide, SGLT-2 inhibitor dapagliflozin and their combination in patients with type 2 diabetes and micro- or macroalbuminuria.Secondary objectives are…
To compare the antiproteinuric effects of sacubitril/valsartan (ARNI) and valsartan (ARB).