12 results
Overall objective:The overall objective is to test the hypothesis that GLP-1 receptor activation of CNS reward and satiety circuits occurs, in the context of food(-related) stimuli, and that this effect is altered in individuals with obesity and…
To study the adaptive capacity in relevant metabolic processes after a high fat challenge and oral glucose challenge in humans. It is expected that a test method that is generally applicable in clinical food research can be developed.
The presently proposed study aims to investigate how dairy proteins compare to vegetable protein and carbohydrate sources leads to glucose and insulin metabolism and substrate partitioning.
The presently proposed study aims to investigate how different feeding frequencies lead to differences in glucose and insulin metabolism in impaired glucose tolerant (IGT) men.
The aim of this study is to determine whether subcutaneous administration of insulin detemir, as compared to NPH insulin, leads to a more pronounced effect on brain glucose metabolism and blood flow in brain regions associated with appetite…
The presently proposed study aims to investigate the effect of feeding frequency on glucose and insulin metabolism and substrate partitioning.
The main objective is to elucidate the acute effects of an oral intake of either saturated, monounsaturated or polyunsaturated fatty acids on PBMC whole genome expression of obese and type 2 diabetic obese subjects. Secondary objectives are to…
To study the role of central insulin on glucose metabolism.
The presently proposed study aims to investigate the effects of different dairy products, which are frequently used in the Netherlands and not yet analyzed, on Glycemic Index and Insulin Index in humans. This will be investigated by analyzing…
The primary objective is to assess whether the insulin-stimulated glucose uptake in quadriceps muscle can be improved through 4 weeks of supplementation of clenbuterol.
To assess the acute impact of passive heat treatment on the post-prandial glycaemic response during an OGTT in T2DM patients.
To determine if short-term treatment with the selective beta-2-adrenergic agonist clenbuterol improves glucose disposal via the mTORC2 pathway in lean, healthy male individuals with normal physical activity