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A randomized, double-blind, placebo controlled, crossover study to determine the effect of 5g egg protein hydrolysate (NWT-03) on arterial stiffness, microcirculation and blood pressure in otherwise healthy subjects with Metabolic Syndrome

To assess the acute (2h) and short term (2 days and 4 week) effects of daily administration of 5g of NWT03 (an egg-protein hydrolysate) on carotid-radial Pulse Wave Velocity (cr-PWV). Secondary objectives are to assess its effects on carotid-femoral…

The effect of L-arginine on brown adipose tissue metabolism in South Asian and white Caucasian subjects

In this study, we will investigate the influence of the amino acid L-arginine, which enhances release of nitric oxide in the body, on BAT activity and metabolism in healthy subjects with overweight. This will increase understanding on the effect of…

A Double-blind, Randomized, Multicenter Study to Evaluate the Safety and
Efficacy of AMG 145, Compared With Ezetimibe, in Hypercholesterolemic Subjects
Unable to Tolerate an Effective Dose of a HMG-CoA Reductase Inhibitor Due to
Muscle Related Side Effects

Primary objective:To evaluate the effect of AMG 145 administered subcutaneously (SC) once every month (QM) compared with ezetimibe (Part B), on percent change from baseline in low-density lipoprotein cholesterol (LDL-C) in hypercholesterolemic…