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The effect of glycopyrronium bromide on hypersalivation in patients with Parkinson's disease: a randomised, cross-over, double-blind, placebo controlled trial.

The aim of this study is to prove the efficacy of 3 times daily 1 mg glycopyrronium bromide versus placebo in patients with PD with hypersalivation. Furthermore, the safety of glycopyrronium bromide used in the mentioned dosage will be further…

The effect of the STIL brace on forearm tremor - a double-blind randomized crossover study

Primary objective: - To evaluate the effect of the STIL brace on tremor amplitude in patients with forearm tremor. Secondary objectives: - To evaluate the effect of the STIL brace on patients* impressions of tremor severity.- To assess patient…

A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of NBI-827104 in Subjects with Essential Tremor.

- To evaluate efficacy of NBI-827104 in subjects with ET - To evaluate safety and tolerability of NBI-827104 in subjects with ET- To evaluate pharmacokinetics of NBI-827104 and metabolite (if quantified) for each treatment in subjects with ET

Therapeutic effects of an inhaled levodopa dry powder formulation on the recovery from off periods in patients with Parkinson's disease

The primary objective is to determine the time until maximum effect is reached of inhaled levodopa on motor function of Parkinson's disease patients during an off period. The secondary objectives are to determine the clinical improvement of…

Neurostimulation for the treatment of mild cognitive impairment in Parkinson*s disease: an acceptability cross-over study

The primary objective of this study is to assess the acceptability and feasibility of four-week, high-frequency rTMS and anodal high-definition tDCS of the DLPFC as potential intervention methods for the treatment of PD-MCI. Secondary study…