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A randomized, four-way crossover, comparative bio-availability study of branded (Neurontin®) and three generic 800 mg gabapentin labels in healthy subjects under fasting conditions.

The aim of this study is to investigate the possible consequences of generic-generic substitution of gabapentin, a frequently used anti-epileptic drug.

The effect of spinal anesthesia on pain perception and
sedation in healthy volunteers

(1) To assess the effect of deafferentation on pain processing in the brain by task-fMRI(2) To assess the effect of deafferentation on reaction time (sedation) by task-fMRI(3) To assess the effect of deafferentation on endogenous pain modulation

Quantifying various effects of closed-loop Spinal Cord Stimulation (SCS) on pathophysiological mechanisms in Complex Regional Pain Syndrome (CRPS); an explorative study

To evaluate and quantify the various clinical effects of closed-loop SCS versus open-loop SCS on the underlying pathophysiological effects in CRPS.