40 results
We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
The hypothesis formulation for the primary outcome parameter is: -H0: The effect of using test product (Product A) is equal to the effect of using control product (Product B) with respect to the area under the curve (AUC(0-360))of serum P. -H1: The…
We expect that younger children have a higher learning capacity at the end-effector level, thus they should be faster in learning to handle the visuomotor transformation task than older children.
Doxepin hydrochloride 5% cream significantly reduces pruritus in burn patients in comparison with a placebo cream
Patients with ALS are routinely prescribed riluzole, the only registered drug for the treatment of ALS. This study will evaluate the concentration-effect relationship of riluzole (100 mg) and retigabine (300 mg) on axonal excitability measures. In…
It is hypothesized that the outcome of the primary outcome parameter will be different for the test product compared to the control product.
Preterm infants often require supplemental oxygen to prevent hypoxemia and hyperoxemia. Conditions that have been associated with organ damage and an increased mortality. Newly developed techniques incorporated in the ventilator provide the…
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The primary objective of this study is to investigate if a specifically designed VR-game is able to activate the pathophysiological substrate associated with OCD in OCD patients, as opposed to healthy controls. This will be investigated by…
To determine the influence of curcumin and piperine on tamoxifen pharmacokinetics.
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
Improvement in forearm rotation.
We hypothesize that steering DBS will lead to a greater reduction of PD motor symptoms than ring-mode DBS. We will also separately measure the effect of the two types of DBS in people who have good response to ring-mode and those who don’t.
Preoperative planning with x-ray-based PSI have comparable outcome as 3D used MRI-based PSI resulting in indirectly reduced costs on storage of implants and instruments.
The use of a web-based decision aid with value clarification exercises will improve patients' knowledge and will give patients realistic expectations of risks and benefits. Addition of the G8 (frailty instrument) and the Timed Up and Go-test as…
We hypothesize that ketamine stimulates breathing and reverses opioid-induced respiratory depression.
To demonstrate a 25% increase of docetaxel in tumor tissue after intravenous administration of CriPec® docetaxel compared to Taxotere®.
In this randomised, double-blind, placebo-controlled single centre study we propose to study the effect of duodenal infusion of single E. hallii treatment (administered via duodenal tube) on small intestinal gene expression, bacterial composition…
Due to the lack of information about DON absorption and excretion, the aims of this study are the description of the DON and metabolites excretions patterns and know the absorption and excretion rates of it. Moreover, the results can be useful to…
We hypothesize that both nitrate and sucrose will reduce GI damage and improve GI blood flow during high-intensity exercise compared with placebo.