10 results
Main objectivesCohort study:To investigate the prognostic implications of skin sodium accumulation for CKD patients.Sodium excretion intervention study:To study the effect of increased renal sodium excretion, with and without …
This traditional feasibility study intends to inform a future pivotal trial in the following two ways. Firstly, it aims to evaluate the potential of neural health metrics triggered by FMS, to predict the implant recipient*s auditory performance -…
To investigate the impact of different doses of handgrip exercises (moderate vs high intensity) and stimuli (exercise vs ischemia) on the ability to protect endothelial damage from ischemia-reperfusion injury in healthy humans. A secondary goal is…
Primary objective• Assess the ability of donepezil to reverse biperiden-induced effects on adaptive tracking performance at timepoint 4h Secondary objectives• Evaluate the PK of donepezil and biperiden• Investigation of pro-cholinergic effects of…
The primary aim of this study is to investigate the effect of four different degrees of arch support on arch compression and running economy. Moreover, as a secondary aim, this study also examines the effect of bending location on running economy.…
The primary objective of this study is to isolate effects of dopamine receptor manipulation on distinct forms of working memory (WM) gating and their associated physiological changes in distinct layers of prefrontal cortex (measured with high-…
The present study compares the postprandial amino acid uptake kinetics between a commercially available (fermented) yoghurt versus a commercially (full fat pasteurized) milk matched for protein and volume.
Primary Objectives: Quantify the PD effects of CNS active compounds with distinct mechanisms of action (lorazepam, modafinil and S-ketamine) with NeuroKit and NeuroCart in healthy male and female participants. Estimate the…
In this study, we investigate how two new measurement methods can demonstrate the effects of two existingdrugs, modafinil and alprazolam, on the excitability of the brain. We test these effects only in healthy subjects.The effects of modafinil and…
The primary objective is to study whether a microparticulated whey protein shake shows a non-inferior incremental area under the curve (iAUC) of the plasma total essential amino acids (TEAA), up to 300 minutes after protein consumption, compared to…