10 results
The objective of this study is to evaluate the acute effects of sitting on cognitive measures in healthy elderly, and if these effects can be prevented by breaking-up sitting and/or a high mental activity state. In addition, this research explores…
The primary objective of this study is to investigate to what extent hepatic fat oxidation can be stimulated by lowering hepatic glycogen content during a prolonged overnight fast. The secondary objective is to investigate whether reductions in…
To evaluate the effect of a drifting ambient temperature versus a fixed ambient temperature on subjective comfort and sensation, and thermo-physiological parameters. Additionally, the effect of different activity levels on the location of the…
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
The main objective of the study is to investigate whether ciprofibrate treatment can improve myocardial insulin sensitivity in subjects with IGM. As secondary objectives we want to investigate whether ciprofibrate treatment also improves diastolic…
Primary objective is the delta change in whole body insulin sensitivity upon Na-PB vs. placebo treatment. Secondary objectives are muscle mitochondrial oxidative capacity, muscle and liver fat content and energy metabolism.
To investigate the effect of intravenous lactate administration, compared to placebo, on thalamic (regional) and global CBF during euglycemia and hypoglycemia in patients with T1DM and NAH.
To investigate how acute potassium administration affects potassium and sodium balance in healthy subjects as compared to patients at different CKD stages, i.e., normal kidney function and stage 3b/4 CKD.
Pre-pilotfase:To optimize procedures and cost efficiency in the design of the pilot phase, we address the following questions:1. Which systemic factors are most useful to monitor AMD supplement intake?2. Can these factors be measured by finger prick…
To analyze how potassium handling, volume and sodium status change in stable anuric chronic hemodialysis patients (CKD-5D) in response to higher dialysate potassium.