145 results
The use of automated closed loop oxygen control in infants on infants with high flow nasal canulla (HFNC) support, will lead to higher amount of saturations within target range compared to manual control.
The hypothesis is that patients with thiopurine therapy will not be at risk of impaired semen quality.
Effect of hyperbaric oxygen therapy (HBOT) on patients with chronic neurological deficiency due to stroke.
To study gastric emptying of breastmilk and infant formula and to see whether gastric emulsion stability differs between breastmilk and infant formula.
To demonstrate whether hydrochlorothiazide or metformin can diminish aquaresis in patients with ADPKD who are treated with tolvaptan as measured by 24-hour urine volume.
Primary objective: - To measure infraslow EEG changes during stress response in healthy subjects.Secondary objective(s):- To investigate if cortisol levels relate to ISA.- To explore ISA activity as a potential biomarker for stress.- To formulate…
The primary objective of this study is to investigate if the addition of bovine milk fat to an infant-formula product increases the diet-induced thermogenesis. Secondary objectives are to investigate if the addition of bovine milk fat in an infant…
The purpose of the study is to investigate how quickly and to what extent 2 different production batches of alpelisib (FMI and FMIopt) are absorbed and eliminated from the body (this is called pharmacokinetics). In this study it is investigated…
To evaluate postprandial amino acid kinetics in blood, after consumption of (*10 g protein per 100 ml) of different types of dairy proteins (in varying combinations) in small volumes, in an older population
The primary objective of the proposed study is to evaluate the effect of the high dose or L-arginine (3.0 gram) and a lower dose of L-arginine (1.5 gram) compared with a placebo supplement on postprandial vascular function, assessed by brachial…
The purpose of this study is to investigate how safe the new compound JHL1922 is when it is administered to healthy subjects. JHL1922 has not been administered to humans before, but it has been previously tested in the laboratory. In this study, the…
To study the effect of TRH on opioid-induced respiratory depression in healthy volunteers.
The main objective of this study is to determine whether creatine monohydrate supplementation enhances diet-induced thermogenesis and brown adipose tissue activity in young, healthy adults, as quantified through PET-MR, following an acute cold…
The main objective of the study is to determine the albuminuria lowering effect of the GLP1-RA exenetide, SGLT-2 inhibitor dapagliflozin and their combination in patients with type 2 diabetes and micro- or macroalbuminuria.Secondary objectives are…
• To determine the profile of CNS effects at several time points after 2 mg and 4 mg biperiden in comparison to placebo in healthy elderly subjects.• To investigate the safety and tolerability of biperiden in healthy elderly subjects.• To determine…
Primary* Evaluate the effects of BMS-986231 on the left ventricular (LV) systolic function by stroke volume index (SVI) assessed by echocardiography compared to placebo. Secondary* Evaluate the effects of BMS-986231 on the left ventricular (LV)…
To study and evaluate the plasma concentration-time curves in health young women of free EPA and DHA, as well as those present in a fish oil food supplement (predominantly esterified to glycerol and/or as ethyl-esters) of their esters, following an…
In short it is widely accepted that EMDR is effective in treating PTSD. EMDR however is not commonly used in treating PTSD patients when there is a comorbid BPD, even though it has been proven that PTSD can be successfully treated when people suffer…
To examine whether a short or longer period on a ketogenic diet leads to an altered immune response after exercise.
We aim to study what the mean change in graft flow rate is when the cardiac output is increased with 10% and what the mean change in graft flow rate is, when the blood pressure is increased with 10% to enable further research to establish whether an…