384 results
We would like to eludicate the role of dopamine on glucose metabolism.
Primary Objective: To determine the effect of breakfast replacement by a low-glycemic index liquid meal on fasting and postprandial glucose and insulin concentrationsSecondary Objective(s): To determine the effect of breakfast replacement by a low-…
Objective of the study is the comparison of two previously developed computeralgorithms for the artificial pancreas (closed loop). One algorithm developed by a researchgroup in Cambridge UK, and an algorithm developed by research groups in Padua and…
Cholesterol absorption inhibition (%) calculated from plasma concentration vs. time curves from labeled cholesterol, for the PS or PSE containing products, compared to a control product without PS or PSE.
to measure peripheral insulin sensitivity and intramyocellular concentrations of different FA metabolites (ceramide, gangliosides, diacylglycerol and triacylglycerol) known to interfere with the insulin signalling cascade during infusion of…
The primary aim of the study is to determine the effect of orally administered AZD2516 as a reduction of the number of reflux episodes, in comparison with placebo, over a period of approximately three hours after a meal, in healthy male volunteers.
It will be investigated whether there is a difference in amount, kind and intensity of normal daily activities between wearing a prosthesis in comparison with not wearing a prosthesis in patients with transtibial and transfemoral amputations. The…
The primary objective in this study is to compare the effectiveness of lateral C1-2 pulsed radiofrequency application (LPRF) in comparison with conventional C3-5 facet denervation (MBRF) in patients with clinically defined cervicogenic headache.
The primary objective in this study is to evaluate effectiveness of optimized high cervical epidural neurostimulation against placebo-stimulation in patients with intractable cervicogenic headache in a neurostimulation trial.
The main objective of the present protocol is to investigate to what extent oxytocin modulates specific aspects of approach behavior and action control in healthy volunteersResults from this study shall give rise to designing a future study on the…
Our primary objective is to determine the effect of Salvia miltiorrhiza extract (Danshen) on hyperlipidemia, in particular LDL-cholesterol. Secondary objective is to investigate the effect of Danshen on hypertension. Further objectives are to…
The primary objective of this study is to evaluate the tolerance of a new smoothie-style paediatric sip feed compared to a standard paediatric sip feed for a period of 6 weeks in children in need of oral nutritional support. The secondary objectives…
The primary objectives of the study is to test the hypothesis that in healthy volunteers RIPC (bilateral forearm ischemia and reperfusion) reduces troponin I appearance in plasma in response to a high intensive bicycle exercise test.
Primary Objective: 1. Will an exposure to oxygen with a PO2 = 190 kPa lead to changes primarily in DLno compared to DLco?Secondary Objectives: 1. After an exposure to oxygen with a PO2 = 190 kPa for one hour, are the changes primarily located in the…
To measure serum insulin and glucose profiles after bolus insulin administration by a patch-pump versus a catheter based pump, reproducibility of these insulin profiles and the effect of catheter wear-time on these profiles in patients with type 1…
Primary objectives:1) Describe the PD effects on plasma ACTH and serum cortisol upon 100 µg hCRH injection with or without a preceding injection of 10 µg dDAVP 2 hours earlier and study the PK-PD relationship (*Block B*). In particular, the outcome…
The aim of this research is to determine the effect of glucose in the small intestine on the secretion of hormones, appetite related feelings and food intake, and whether these effects differ between time of day (morning vs evening) and segment of…
•To determine the effect of short-term Topiramate treatment on glucose metabolism including endogenous glucose production, whole body glucose disposal and glucose oxidation in obese women. •To determine the effect of short-term Topiramate on lipid…
To investigate the effect of specially bred snack cucumbers (Trees) intended for human consumption on glucose homeostasis in comparison to common snack cucumbers (Cucumis Sativus) after OGTT in obese individuals.