51 results
The main objective is to investigate the preparatory process in left primary motor cortex in relation to hand choice during whole-body motion.
To test an acellular dermal template (Novomaix) in human patients in need of full thickness skin defect coverage and to compare the results with those obtained after conventional STSG. The main goals are to study the efficacy and scar quality after…
The effect of pulse rate on temporal resolution and speech intelligibility in cochlear implant users
To determine the (in)direct effect of CI pulse rate on speech intelligibility by means of (1) a standard test for temporal resolution: amplitude modulation detection (AMD) at two different modulation frequencies, (2) speech intelligibility tests (…
Primary objectives:The primary objectives of this trial are:• To show PK similarity of BI 695500 to MabThera® and Rituxan® and of Rituxan® to MabThera® (three-way PK similarity).• To establish statistical equivalence of efficacy of BI 695500 and…
The main purpose of this study is to find out whether EMDR is a safe and effective treatment to reduce the symptoms of PTSD in people with mild intellectual disability and borderline intellectual functioning. In addition, it is expected to reduce…
Primary objective of the study is to record TIP inhalations on video at home to study the association between inhalation manoeuver and cough. Secondary objectives are: To study the inhalation maneuvers of patients using TIP in the home situation; to…
The aim is to critically evaluate the additive effect of EMDR to ERP on treatment acceptability, drop-out, and outcome; a) does EMDR lead to a decrease in OCD related memory representations (or in other words; does it lead to a decrease in the…
Primairy objective:• To determine the safety, tolerability and pharmacokinetics of 2B3-201, and in comparison to free methylprednisolone hemisuccinate and placebo;Secundairy objective:• To determine the pharmacodynamic effects of 2B3-201 on CNS…
The primary objective of this study is to investigate the effect of itraconazole on thepharmacokinetics (PK) of olaparib following oral dosing of the tablet formulation inpatients with advanced solid tumours.The secondary objectives are: to…
With this study, we aim to evaluate precision and practicability of three new measurements for (venous) Hb, as compared with the present standard.* Precision will be studied as sensitivity and specificity of the measurements for a venous Hb under…
The primary objective of our study is to investigate the performance of FCH-PET as a second-line imaging modality for localizing hyper-functioning parathyroid gland(s) in patients with biochemically proven PHP for whom surgery is indicated, thereby…
The primary objective of this study is to investigate the effect of food on the pharmacokinetics(PK) of olaparib following oral dosing of the tablet formulation in patients with advancedsolid tumours.The secondary objectives are to investigate the…
Therefore we decided to conduct a prospective randomised clincal study comparing these two donor sites (calvarium and iliac crest) with respect to bone volume changes and bone formation.Primary Objective: to know what the changes in bone volume are…
The primary objective of this study is to describe a pharmacokinetic profile of bound and unbound plasma concentrations of ropivacaïne, when used in the LIA technique for the knee. Especially describing the Cmax and Tmax gives arguments for dosage…
The main aim of this study is to identify the neural correlates of four kinds of spatial representations, i.e. egocentric coordinate, egocentric categorical, allocentric coordinate, and allocentric categorical, in both visuo-perceptual and visuo-…
Gaining insight in the modulating effects of attention on the processing of short electrocutaneous painful and non-painful stimuli by comparing the patterns in brain activity en subjective measurements during different conditions of attention.…
Aim of this study is to investigate the clinical performance of two restoration techniques, making use of 'direct' and an 'indirect' composite restorations as a minimal invasive intervention in patients with severe tooth wear.…
The objective of the current study is to investigate the effect of mindfulness training on attention shifting in a pain setting. This question will be tested in an experimental design. Outcomes of the study will be used to further investigate…
(1) Investigate diagnostic performance (sensitivity) of HD bronchoscopy, with or without surface enhancement or tone enhancement in comparison to standard WLB for detecting abnormalities of the tracheobronchial tree. Furthermore we aim to…
To investigate inter-examiner variability of the alternate prism and cover test (APCT) measurements of ocular deviation at near and distance fixation, and to compare variability between adults/teenagers and children.