204 results
Various brain areas play a crucial role in both pain and cognition, supporting the existence of a close relationship between pain and cognition. Consequently, it is important to examine whether pain experience changes at the moment the patient shows…
Development, optimization and implementation of retro-orbital fibroblast cultures in our laboratory.
This study aims to identify the relationship between candidate genes such as for instance BDNF, 5-HTTLPR, DAOA, G72, DTNBP1, NRG1 and COMT with cognitive function and emotional- and behavioural traits.
ObjectiveEvaluation of the application of cultured autologous keratinocytes in combination with a meshed split skin autograft to improve burn wound healing
The aim of this study is assessment of right ventricular function: a comparison between MRI and real-time 3-D echocardiography (RT 3-D echo). We have the following research questions: 1) Is assessment of right ventricular (RV) function with RT 3-D…
The objective of this study is to identify determinants, to determine the transmissibility and to determine the burden of disease of NT-MRSA and CA-MRSA carriage compared to other typeable MRSA strains in the community.
The research is set up to investigate three primary questions.1. Is there a difference between bone resorbing capacity between postmenopausal women with a vertebral fracture and postmenopausal women without a vertebral fracture and high bone mineral…
The aim of the study is to assess the feasibility of combined treatment of Cisplatin, Cetuximab and concurrent RT and to get insight in the clinical efficacy (for study schedule, see flow chart 1). The first phase of the study will mainly focus on…
To identify an AAA associated genes by a functional candidate gene approach.The identification of an AAA associated gene will have several impacts on this high prevalent disease:1. It will improve our understanding of the molecular pathways involved…
Within the observational study WP9, there will be 3 substudies. First the microbiological aetiology of LRTI will be studied by comparing test results in 3000 healthy controls to findings in 3000 adults with LRTI. Bacterial resistance rates will be…
To investigate the effectiveness of family meetings on indicated prevention of anxiety and depressive disorders (DSM IV) and symptom levels of primary family caregivers of patients with dementia. To perform an economic evaluation alongside the trial…
In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…
Aim of this study is to explore the relation between Th1-cell mediated diseases as psoriasis/psoriatic arthritis and Th2-cell mediated asthma, allergic rhinoconjunctivitis, atopic dermatitis and hand eczema. Question is whether a dysbalans in…
The overall aim of the study: To assess whether an exercise program can improve insulin sensitivity and fasting plasma glucose levels of women at high risk for gestational diabetes, assuming that this will normalise their risk of gestational…
Primary:To validate the latest version of DySIS in discriminating high grade (HG) from low grade (LG) lesions and non neoplastic tissue as well as in selecting the most atypical site for biopsy sampling, through digital documentation and…
Is it possible to improve routine detection and treatment of osteoporosis after an initial fracture?I) is it possible to increase the proportion of patients adequately screened and categorized as to the presence of osteoporosis from current practice…
Core:1. Quantify vigilance using a portable task battery three times daily during 7 days while subjects are outside the hospital 1.1 Comparing narcoleptic patients to controls 1.2 Comparing narcoleptic patients before and after treatment with sodium…
The aim of the current study is to investigate the effectiveness of the psycho-educational program started at nursing home Klevarie for stroke-patients and their caregivers in expanding their: knowledge about a stroke and its consequences;…
We need objective and validated tests for the assessment of the severity of impairment in CFS/ME patients. In 2 areas these tests will be essential: for studies of the effect of interventions and for the assessment of disability.Hardly any research…
The objective is to analyze whether a difference in reservecapacity is present between short-term and long-term PD patients. In case the reservecapacity of the peritoneum is significantly lower in the long-term compared to short-term PD patients, a…