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The changing over time of ascorbic acid after chemotherapy and the correlation between ascorbic acid and the recovery of the immune cells after chemotherapy in patients receiving intensive clinical chemotherapy for acute leukemia and high dose chemotherapy with autologous stem cell rescue and in outpatients receiving relatively mild chemotherapy for lung cancer and colon cancer.

The aim of this study is to evaluate the changing over time of AA levels in plasma and in leukocytes before and during chemotherapy treatment for several different groups of patients and compare that to healthy controls.