18 results
The objective of the current proposal is to further explore the pathophysiological changes that occur in patient with an IGSF1 mutation, using an established method for assessing hormone secretory characteristics.
to find evidence for frontal inhibition during planning of explicit movements just as seen in patients with conversion disorders.
To understand, from the perspective of the 3-hit hypothesis of psychopathology, individual differences in the neuropsychiatric outcome of previous glucocorticoid (GC) excess in treated Cushing patients.
• To investigate if FD in CRPS is associated with specific structural and functional changes of the brain.• If so, to find out which of these changes are specific for FD in CRPS, i.e., independent regardless the clinical setting (pain versus…
The goals of the present study, therefore, are twofold:a) To estimate the incidence of dream/reality confusions in the narcoleptic population, relative to healthy controlsb) To provide a comprehensive description of the characteristics of these…
Objectivesi)) To study whether reproductive hormones play a role in migraine susceptibility in malemigraine patients; ii) to study functionality of the trigeminal system prospectively duringinterictal and premonitory phases of the migraine attack (…
• To construct the pedigree of patients with SCCH with special attention to the presence of other inflammatory disorders such as inflammatory bowel disease, psoriasis, inflammatory arthritis in patients and kindreds.• To identify the gene mutation…
1. Are there differences between patients and controls in circadian movement rhythmicity and sleep duration?2. Are these objective measures associated with subjective sleep complaints?3. Are these objective measures associated with decreased quality…
Does HLA sharing in couples with recurrent miscarriage play a role in recurrent miscarriage of unknown etiology?
What values are normal in healthy controls for endurance and force? Are these values the same for men and female? What is the effect of age to these normal values? What are endurance and force for patients with myasthenia gravis? Are there specific…
In this project, I wish to take a novel step in understanding the influence of environmental exposures in the aetiology of psychotic disorders, by studying occurrence of (minor) psychotic symptoms and the (correlates of) physiological indicators of…
Primary Objective: To identify immuno-endocrine and neuro-imaging parameters differentiating between different mood states (manic, depressive, and euthymic). Secondary Objectives: 1. To identify the influence of these parameters on the onset and…
The primary objective is to determine and compare the microvascular status between middle-aged women with and without migraine. Secondary objectives include a determination of the agreement and reproducibility of two devices which measure the blood…
The primary objectives are to: (1) Examine whether emotional incongruence (i.e., the mismatch between self-reported emotion and observed emotion from facial expression) is more common in patients with FND than non-FND control groups (healthy…
To assess changes in food intake and food preference (e.g., fat and sugar) after bariatric surgery.
The primary objective of this study is to develop a method by which large numbers of immune cells can eventually be obtained from a kidney biopsy to study phenotype and function of immune cells and unravel mechanisms contributing to loss of renal…
Overall aimIdentify immunologic imbalances, with a focus on IFN, NETs, complement and lymphocyte subsets during pregnancy in women with systemic autoimmune diseases.HypothesisWe hypothesize that increased IFN activation and NET formation in patients…
Primary Objective: The primary objective is to compare GABA concentrations and receptors availability in the auditory pathway between individuals with tinnitus and two control groups without tinnitus (with or without hearing loss). GABA…