18 results
Evaluation of quality of life and resoration of function after bile duct injury.
The study objective is the assessment of influence on glucose homeostasis as a consequence of starting switching, discontinuing or doses changes with antidepressants in a population of diabetic patients.
The aim is to investigate the effect of a multimodal prehabilitation and rehabilitation program in frail patients of 70 years or older, undergoing elective surgery for non-metastatic CRC on1. One-year mortality 2. Postoperative complications,…
To evaluate whether a less radical surgical approach with sentinel lymph node biopsy is non-inferior to treatment with systematic pelvic lymphadenectomy.The null hypothesis is that the recurrence rate after SLN biopsy is non-inferior to the…
The goal of this study is to examine the feasibility of a home-based VR intervention to improve upper limb functionality in patients with CP. Primary research question: 1. Is VR-based gaming a feasible method to provide a rehabilitation intervention…
Primary Objectives- To evaluate disease-related characteristics and biomarkers in patients with CLE compared to healthy volunteers. Secondary Objectives- To evaluate the variability of the selected biomarkers between patients - To investigate the…
In this study we will investigate how safe the new compound LEO 158968 is and how well it is tolerated when it is used by healthy subjects.We also investigate how quickly and to what extent LEO 158968 is distributed and eliminated from the body. In…
This study has been transitioned to CTIS with ID 2023-507052-69-00 check the CTIS register for the current data. To evaluate the long-term safety and tolerability of ARGX-117 in adult participants with MMN
Primary Objective: For the primary objective, the following research question is answered: Does performing asleep thalamic DBS provide an equal reduction in tremor compared to awake thalamic DBS, measured by the Essential Tremor Rating Assessment…
The aim of this this study, is to test whether EMDR therapy, relative to a baseline phase, results in: 1) less social anxiety symptoms, and 2) less social avoidance symptoms
This study has the following study aims: 1) Investigate whether treatment context and the addition of chronotherapeutic and social rhythm interventions improve the efficacy of BLT, 2) examine the role of circadian phase resetting and changes in…
To determine the prevalence of taste and smell dysfunction in patients more than two years after start of ICI therapy - compared with a control group of caregivers. Secondary objective: to assess the association between taste and smell dysfunction,…
Primary:• To evaluate the proportion of patients with obesity with genetic variants in a specific gene in the melanocortin-4 receptor (MC4R) pathway who achieve a clinically meaningful reduction in body weight in response to setmelanotide at the end…
This study has been transitioned to CTIS with ID 2024-515487-31-00 check the CTIS register for the current data. The primary objective of this study is to describe the pharmacokinetics of antiretroviral agents, for which no or limited available…
This study has been transitioned to CTIS with ID 2024-512190-27-00 check the CTIS register for the current data. To evaluate the efficacy and safety of EHSG-KF in comparison to STSG (unmeshed or meshed up to 1:3) in adults and children with large…
1. Provide evidence for the clinical effectiveness of dCBT-I for the treatment of insomnia symptoms in pregnant woman with psychiatric vulnerability. 2. Provide evidence for the effectiveness of insomnia treatment and the positive effects on mental…
The primary objective is to compare the accuracy of the five-dimensional (5D) calibrator device for glenoid positioning with the accuracy of the conventional (freehand) method.
The aim of the current study is to 1) investigate what the effects are of a condensed, intensive outpatient exposure treatment in patients with OCD who are not sufficiently improved from standard CBT (ERP) and 2) to map early indicators regarding…