11 results
The primary objective is to develop algorithms that define digital biomarkers for disease progression in Progressive Supranuclear Palsy patients. The biomarkers, when developed systematically, can eventually serve as primary or secondary clinical…
To study the long-term changes in DNA methylation and gene expression in sepsis survivors and their association with long-term morbidity and mortality after sepsis.
The goal of this study is to examine the feasibility of a home-based VR intervention to improve upper limb functionality in patients with CP. Primary research question: 1. Is VR-based gaming a feasible method to provide a rehabilitation intervention…
Primary Aim: We aim to determine markers for NOX2-mediated insulin-independent glucose uptake signalling pathways, mitochondrial function, myokine secretion both at rest and after a bout of acute exercise in individuals with T1DM and healthy…
Development of a diagnostic algorithm that will diagnose measles cases and classify (potential) contagiousness of patients following measles infection.
The first objective is to investigate who the PMSA are, what strategies and motives they use to approach minors online, what sexual activities they do on the Internet and whether they are satisfied with their (sexual) wellbeing. The second objective…
The goal is to develop and research the smartphone app intervention to adolescents with a chronic medical condition 1) to offer an intervention with attractive and fun challenges to increase their emotional resilience and2) to identify emotional…
Primary:• To evaluate the proportion of patients with obesity with genetic variants in a specific gene in the melanocortin-4 receptor (MC4R) pathway who achieve a clinically meaningful reduction in body weight in response to setmelanotide at the end…
To assess the antibody response after SARS-CoV-2 vaccination in people >=16 years and children with Down Syndrome. Part 2To assess the antibody response after a third SARS-CoV-2 vaccination in adults and children with Down Syndrome and to…
The primary objective is to compare the accuracy of the five-dimensional (5D) calibrator device for glenoid positioning with the accuracy of the conventional (freehand) method.
1. Provide evidence for the clinical effectiveness of dCBT-I for the treatment of insomnia symptoms in pregnant woman with psychiatric vulnerability. 2. Provide evidence for the effectiveness of insomnia treatment and the positive effects on mental…