14 results
Primary • To assess the efficacy of relacorilant for the treatment of endogenous Cushing syndrome based on BP control at Week 12 of the Randomized- Withdrawal (RW) phase compared with placebo• To assess the safety of relacorilant for the treatment…
This study has been transitioned to CTIS with ID 2024-514612-27-01 check the CTIS register for the current data. The primary objective is to measure the level of clinical improvement and quality of life at 3, 6 and 9 months compared to…
The primary objective of this study is to confirm early and subtle MRI changes in PD patients which distinguish them from the healthy population and to create a diagnostic tool for neurologists based on these differences. Secondary objectives are to…
This study has been transitioned to CTIS with ID 2024-517922-24-00 check the CTIS register for the current data. Although DC vaccinations have been used in allo-HCT settings, no previous studies have been performed using a CBDC vaccine after CBT.…
We will assess the (cost-)effectiveness of implementing two interventions in the birth centre setting:1. TcB measurement as a non-invasive screening tool to identify jaundice.2. Application of phototherapy in the birth centre.We hypothesise that…
General- To compare physical activity levels of pediatric patient subjects with healthy control subjects.- To compare mean heart rate and variation in heart rate during the day of patients and healthy controls.- To compare sleep duration of patients…
- To determine a mean recovery period for patients admitted with pneumonia, bronchiolitis, preschool wheezing and asthma by using data obtained during admission and via home-monitoring of a two week period following admission and control period and…
To assess utility and accuracy of an electroencephalography (EEG) -based brain network analysis platform as potential diagnostic tool for MDD, to correlate digital biomarkers and *gold standard* psychometric questionnaires such as MADRS in MDD and…
Primary Objective* To explore the efficacy and pharmacodynamic effects of omiganan topical gel in facial seborrheic dermatitis Secondary Objectives* To explore skin and faecal microbiome in patients with seborrheic dermatitis * To evaluate the…
To investigate the short-term (3 months) effectiveness on physical functioning, and the long-term (24 months) cost-effectiveness, of a personalized stratified blended care intervention (e-Exercise LBP) in comparison with usual physical therapy in…
* To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use;* To determine if therapeutic concentrations achieved with…
Primary objective:1. To explore the effect of flushing after HIPEC on tissue platinum exposureSecondary objectives:1. To explore the effect of flushing after HIPEC on wound exudate platinum concentration2. To explore the effect of flushing after…
Main objective is to compare the incidence of subclavian vein thromboses after TLE by manual traction alone versus TLE with use of the mechanical rotational dilator sheath in case of fibrous adhesions hampering extraction by manual traction alone.…
Research on e-liquid flavors could be performed through smelling or tasting (*vaping*) experiments. The main objective of the Smell-e study is to determine if there is a correlation between liking of e-liquid flavors through smelling and liking of e…