17 results
The primary objective is to identify clinical and biological measures that discriminate paediatric ME/CFS and post-COVID patients from healthy controls based on either clinical (based on physiological tests and questionnaires) and biological (based…
The aim of this study is both a feasibility study to gain a comprehensive understanding of the feasibility, satisfaction and impact, and trends of the effects of a physical exercise and nutritional intervention in patients who will be treated by a…
The primary objective of phase 1 is to validate a new ELISA measurement that can determine hIAPP oligomers reliably in plasma, and of phase 2 is to correlate pathogenic oligomer hIAPP (in plasma and skin) with pain and sensory disturbances in CIAP…
The primary objective of this explorative study is to investigate the effect of 3-month preparation period of regular walking exercise prior to the Nijmegen 4-Day marches on objectively measured AF burden (primary parameter), self-reported AF burden…
Primary objective: To longitudinally characterize alterations in electrophysiological biomarkers in ALS of peripheral excitability in relation to neurodegeneration. Secundary objectives:1. To determine the value of multi-muscle CMAP-scan outcomes as…
To evaluate the efficacy of a new tumor-agnostic ctDNA assay, the ctDNA estimator, to detect newly developing tumors in Lynch carriers.
Máxima MC is organising this study. The aim of the study is to gain insight into the effect ofdifferent treatments (medication, IUD, endometrial ablation, uterus removal) formenstruation-related complaints on labour and educational participation.…
The purpose of this study is to investigate the feasibility of introducing a new practice in the Emergency Department for patients who may be problematic users of prescription opioids. This involves using a questionnaire, a short motivational…
The aim of this study is to compare oxycodone and morphine as the first-choice opioid for postoperative pain after orthopedic surgery regarding: The proportion of patients with new long-term opioid use (>6 months). The total proportion of…
Primary To evaluate the prevalence of specific immune cell subsets in a range of IMID dermatologic disease patients, both between diseases and compared to healthy volunteers Secondary To evaluate the variability in specific immune cell…
In this study we want to investigate whether the target group is reached well with this intervention, how patients and healthcare personnel experience the intervention and whether it has an effect on alcohol and healthcare use and participation in…
We want to remap the entire bacterial ecosystem in the gastrointestinal tract of patients with lgA nephropathy after a period of roughy two years, in order to gain insight into the processes that may play a role in the development and progression…
Determine the optimal set of implementation strategies to introduce ERATS in the Netherlands; evaluate whether high protocol adherence indeed leads to the expected reduction in length of hospital stay, complications, and readmissions, alongside…
The primary aim is to determine the length of hospital stay after trauma in patients admitted with one or more rib fractures, who used versus who did not use the Breazy app. The secondary aims are to determine: 1) rate of pneumonia within 30 days; 2…
Primary Objective:The primary objective to create a machine learning model based on biomarkers analysed in EEG-responses during various types of visual stimulation that could aid in the identification of EEGs of people with epilepsy and healthy…
To investigate the (cost-)effectiveness of COD compared to RFU at 1 year, up to 2 years after THA and TKA.
The primary objective of this project is to evaluate the differences between a wide variety of cardiac disease and healthy volunteers using novel echocardiographic techniques (LV SV-loops, 3D RV beutels and SWI) and relate these to patient…