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Nipple sensitivity after prophylactic nipple-sparing mastectomy compared to healthy BRCA1/2 gene mutation carriers.

The aim of this study is to objectify nipple-areola complex sensitivity in women who underwent unilateral or bilateral prophylactic NSM in Erasmus MC-Daniel den Hoed Cancer Center and their satisfaction with this operation, compared to healthy women…

Inamed 410 Silicon-Filled Breast Implant European MRI-Study

proof of safety of the Style 410 silicon breast implants

Clinical Outcome of Postoperative Mediastinitis: Sternal Closure Versus Conventional Treatment

The aim of this study is to compare the clinical outcome and survival in patients undergoing sternal closure treatment or conventional treatment for postoperative mediastinitis. The secondary objective is to determine incidence of mediastinitis and…

ASICS trial: Avoiding Sentinel lymph node biopsy In select Clinical node negative breast cancer patients after neoadjuvant Systemic therapy

The primary objective is to evaluate whether SLNB can safely be omitted in breast cancer patients with HER2+ or TN tumors who achieve rCR on MRI after NST. Secondary, quality of life will be assessed in patients with and without SLNB.

The effect of Hyperbaric OxygeN therapy on brEast cancer patients with late radiation toxicitY

To assess whether HBOT reduces pain, and improves physical functioning and QoL in breast cancer patients with late radiation toxicity.

Pilot study on the use of a radiopaque hydrogel during breast conserving surgery with full-thickness closure for target definition and positioning of boost or partial breast irradiation.

Primary objective: Estimate the Conformity Index (Cx) of target definition. Secondary objectives: Estimate the distance between the center of mass (dCOM) of the observers* target volumes, Cavity Visualisation Score (CVS), feasibility of the hydrogel…

Breast conserving therapy using Accelerated Partial Breast Irradiation (APBI) in elderly patients: a feasibility study

Confirm favorable treatment results of international studies.Relate (loco regional) tumor control, side effects and (inter current) death to geriatric questionnaires/condition, co-morbidity and usage of medication.