19 results
Primary objective: - To study the pharmacokinetics of acetaminophen and metabolites in morbidly obese patients and compare with normal weight patients. Secondary objectives: - To compare the pharmacokinetics of acetaminophen and metabolites in…
To assess whether close rectal restorative proctocolectomy with IPAA has a better outcome regarding postoperative vaginal vasocongestion and reported psychological and sexual functioning then IPAA by TME restorative proctocolectomy.
Main objective is to examine the preliminary effectiveness of preoperative IMT high-intensity in patients undergoing oesophagus resection on postoperative pulmonary complications, inspiratory muscle strength/endurance and IC stay compared to…
To identify differences in the mechanisms leading to dysphagia after laparoscopic Toupet and Nissen fundoplication.
To compare endoscopic transmural debridement with standard conservative treatment in patients with symptomatic sterile organized pancreatic necrosis in a randomized controlled trial with emphasis on extent and duration of recovery.
This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm. In addition, an economic evaluation of the new…
Determine the feasibility of a study on the effectiveness of an integrated physiotherapy strategy aimed at promoting healthy physical activity during and after hospitalization. If the pilot project proves to be feasible, a multicenter randomized…
The hypothesis is that obstruction at the level of the minor papilla is one cause of RAP in pancreas divisum; miES will relieve the obstruction, thereby reducing the risk of a recurrent attack(s) of acute pancreatitis.
The aim is to investigate the effect of a multimodal prehabilitation and rehabilitation program in frail patients of 70 years or older, undergoing elective surgery for non-metastatic CRC on1. One-year mortality 2. Postoperative complications,…
We want to compare the effectiveness of sclerotherapy and rubberband ligation when it comes to symptoms. We will secondarily consider patient satisfaction, complications and recurrences. We hypothesize that both treatments are equally effective.
The aim of this study is to reduce the need for colectomy and its* associated morbidity and mortality in patients with high-risk pT1 or low-risk pT2 colon carcinoma after endoscopic polypectomy by performing a (robot-assisted) laparoscopic wedge…
To assess the effect of a Roux-en-Y gastric bypass on the pharmacokinetics of a single oral dose of 1000 mg paracetamol before the surgery. within one month after the surgery and 6 months after the surgery.
The main objective of this study is to improve surgical and oncological outcomes for patients with right-sided colon cancer by conducting a prospective sequential interventional cohort study that aims to evaluate national implementation of the LRHC…
To study the effect of Liraglutide (3.0 mg daily) on 9-month weight loss in low responders 3-months after bariatric surgery.
Investigate whether the use of the Hot AXIOS lumen apposing metal stent is superior to standard plastic pigtails stents for drainage of infected pancreatic necrosis.
This study has been transitioned to CTIS with ID 2024-517410-15-01 check the CTIS register for the current data. The aim of this study is to determine the oncological safety, treatment related morbidity, and the functional outcome of local excision…
To assess the effect of a Roux-en-Y gastric bypass on the pharmacokinetics of a single oral dose of 1000 mg paracetamol
There is evidence however that abdominal wall blocks, such as TAP blocks, could help managing the postoperative pain, but covering the visceral pain is not possible with this technique. It is not even clear to date which component of pain, the…
Primary objective:1. To explore the effect of flushing after HIPEC on tissue platinum exposureSecondary objectives:1. To explore the effect of flushing after HIPEC on wound exudate platinum concentration2. To explore the effect of flushing after…