100 results
The main objective of this study is to compare upper extremity dysfunction following slender TRPCI using small bore catheters (*5F) compared to standard PCI using regular size guiding catheters(*6F) and conventional stent techniques. Secondary…
To evaluate the effectiveness of selective intracoronary hypothermia in patients with anterior wall ST-elevation myocardial infarction to limit reperfusion injury and to limit infarct size.
To investigate the role of the immune system in the etiology and prognosis in an acute ischemic stroke (or TIA) in young stroke patients.
The objective of this study is three-fold: 1) Assess measurement settings and develop the data processing chain to detect contrast signals in the left-ventricular wall with contrast-enhanced high-frame rate echocardiography. Determine whether this…
Problem definition and objectivesThe microcirculation can only be measured by coronary blood flow parameters during catheterization. Patients with MVD will be offered an unique first in man non-invasive therapy namely: external low intensity shock…
Primary Objective: To assess whether patients with atherosclerosis have more uptake of 68Ga-Dotatate than patients without atherosclerosis. Secondary Objective(s): To correlate 68Ga-Dotatate uptake with the fat attenuation index (FAI), a specific…
1. To investigate whether the TIMELY intervention is superior to usual care in terms of A) reducing the CoroPredict risk score (indicating risk of 10-year mortality: primary biomedical outcome) from baseline to six months; andB) increasing…
The primary objective is to compare a composite endpoint of major CV events and all-cause death between control and intervention group.Secondary objectives are the comparison of patient-centered outcomes between the two groups.
This study has been transitioned to CTIS with ID 2024-518890-33-00 check the CTIS register for the current data. To determine if clopidogrel treatment can be optimized in patients with a low or high BW/BMI compared to patients with a normal BW by…
This study has been transitioned to CTIS with ID 2024-515893-29-01 check the CTIS register for the current data. To study whether ziltivekimab therapy reduces arterial wall inflammation as assessed by imaging, and reduces the systemic inflammatory…
Primary objective: To assess the effect of ICI on progression of coronary non-calcified plaque volume and ICI-related cardiovascular events by measuring differences in plaque burden using repeated CCTA.Secondary objectives:- To evaluate the relation…
To assess whether the in-laboratory strategy is non-inferior to the preloading strategy in patients planned for diagnostic CAG with optional ad-hoc PCI.
To investigate whether MBV is reduced in patients with NOCAD and signs and symptoms of ischemia, relative to healthy controls. The specific aims are 1) to investigate if MBV is reduced in NOCAD patients at baseline, 2) to investigate if MBV is…
CONCRETE aims to: (1) evaluate whether GP access to CT calcium scoring leads to earlier CAD diagnosis and treatment, (2) assess and optimize gender-specific diagnostic stratification based on the calcium score, (3) determine which (cluster of)…
Compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifurcation treatment.
The primary objective of the registry is:To analyse coronary artery disease progression with or without coronary artery bypass grafting.The secondary objective of the registry is:To report graft patency following bypass grafting of diffusely…
The main objective of the current study is to investigate platelet reactivity and underlying mechanisms using the novel multi-microspot analysis in a group of patients with SIHD and a healthy control group.
The primary objective of this study is to evaluate the coronary plaque burden and plaque characteristics in young T1DM patients as compared with non-diabetic healthy controls, using coronary computed tomography angiography (CCTA). The secondary…
The objective of the study will be to analyse the diagnostic and prognostic value of circulating inflammatory and/or coagulation biomarkers in plasma, plasma Extracellular Vesicles (EV), and gene expression profiles of circulating cells for the…
This study aims to investigate the coronary artery system in women with axSpA by examining both morphological and functional parameters, encompassing macro- and microvascular function.