11 results
The main objective is to evaluate the cytokine response to tape stripping in vivo, dynamically and non-invasively by means of patches..The secondary objectives are (i) to correlate the cytokine response with transepidermal water loss (TEWL), a well-…
To investigate whether the T cell profile of T cells in inflamed skin of psoriasis patients is identical or not to inflamedskin/synovium in psoriatic arthritis patients . All this in comparison to healthy controls. By determining the clonality and…
With this study we want to validate the negative pressure instrument which can make suction blisters, so in the future it can be used for other purposes. It can be helpfull to study the effects of medication or other treatments on blister formation…
The aim of this study is to develop and validate the basophil activation test by flow cytometry in our hospital as an extra diagnostic procedure for patients, who can not be diagnosed with existing tests or who have the risk of developing…
To investigate causes and predictors for primary or secondary allergy profiles for soymilk
To test the feasibility of an intended large scale fragrance-allergy prevalence study in the population of the north of the Netherlands and to make a more reliable estimate of the prevalence in the population for poweranalysis of the intended large…
To evaluate the agreement between the results of four diagnostic tests for metal allergy (in vivo patch tests, resp. Lymfocyte Proliferation Test (LPT), a modified LPT (MELISA®), and the Lymfocyte Cytokine Production Test (LCPT), and the clinical…
The aim is to validate the hypothesis that a positive history defined as dermatitis at exposure to a scented product and thereafter avoidance of such products in fragrance-hypersensitive individuals and a positive patch test result to fragrances is…
The study will be designed as a multicenter study to evaluate the impact of several parameters influencing the sensitivity and specificity of skin self tests.The parameters are:- Product applied: hair colouring formula mixed with developer (in use…
Primary Objective:Is there a difference in the cytokine profile of uninvolved skin, perilesional skin and lesional skin of pediatric psoriasis patients on topical treatment (representing mild psoriasis) and pediatric psoriasis patients on systemic…
Primary Objectives- To evaluate disease related characteristics in patients with different vulvar conditions compared to healthy volunteers - To evaluate the variability of the selected biomarkers between subjects, and within subjects over time.…