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MD-PAEDIGREE: Model-Driven European Paediatric Repository - WP 5: Data acquisition and processing for Juvenile Idiopathic Arthritis

To collect demographic, clinical, therapeutic, microbiotic and imaging data in patients with JIA, to build a repository, to find novel biomarkers and to construct computerized models to predict the prognosis in children with JIA af the time of…

ANCA-associated Vasculitis and the Metabolic Syndrom

This study concerns a research that is aimed to investigate the prevalence of the metabolic syndrome in a group of patients known with ANCA-associated vaculitis. Hereby we will compare the presence of the metabolic syndrome between an ANCA-…

The use of a mould in acquisition of hand radiographs improves the reproducibility of scoring of bone erosions and joint space narrowing in rheumatoid arthritis, compared to conventionally acquired images.

To evaluate the reproducibility of the SvdH score (BE and JSN of one hand) of radiographs taken with a mould compared to conventionally acquired images.

CSA cohort Rotterdam

To study patients with clinically suspect arthralgia in order to 1) develop diagnostic/prognostic markers (a. markers of systemic and b. local inflammation as well as c. autoantibodies) for the development of RA 2) to improve the mechanistic…

The interaction between arthritis and the orofacial tissues - prediction and prevention of rheumatoid arthritis.

The primary objective of this study is to assess the prevalence of Temporomandibular Joint Disorders in (1) rheumatoid arthritis (RA) patients, (2) individuals at increased risk of RA, and (3) a control group without autoimmune diseases and to…

MS Self - A study on the validity, sensitivity and user experience of new mobile selfmonitoring devices voor people with Relapsing Remitting Multiple Sclerosis

Technological developments such as smartphones and consumer wearable devices (i.e. the Fitbit) provide novel opportunities for selfmonitoring of people with chronic diseases.Here, we aim to gain insight into the use of these technologies for studies…

Differences in unaffected skin of patients with hidradenitis suppurativa compared with healthy controls.

To compare the microbiome, histology, immunohistochemistry and gene expression profile of healthy skin from the axillae or groin of 10 healthy volunteers with uninvolved axilla or groin skin from age, gender, body mass index, and smoking status…

The role of gutmicrobiota composition, epigenetics and autoimmunity in the development and treatment of vasculitis; the VASKIR biobank

Primary Objective: Primary: Gut microbiota (oral and fecal) and nasal microbiota composition in relation to autoimmunity status (antibodies (ANA, ANCA) and HLA subtype) and inflammatory functional assays as well as disease&…

The DRAIHA study: Data Registry of AutoImmune Hemolytic Anemia, to improve diagnostic testing for the development of personalized treatment protocols in AIHA patients

Primary objective1. The primary aim of the study is to answer the question whether specification of a positive direct antiglobulin test and/or red blood cell autoantibody specification is correlated with the clinical course in patients with AIHA.…

Immunological assessment of SARS-CoV-2 in IENIMINI cohort individuals with influenza like symptoms.

Primary objective: To evaluate, in a cohort of non-tested individuals who reported flu-like symptoms during the COVID19 epidemic in the Netherlands (March-November), the seroprevalence of COVID19 in patients with an IMID, with or without…

An exploratory, non-interventional, single-center study to characterize a set of immune cells in a range of dermatologic diseases

Primary To evaluate the prevalence of specific immune cell subsets in a range of IMID dermatologic disease patients, both between diseases and compared to healthy volunteers  Secondary To evaluate the variability in specific immune cell…