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Re-exposure of previously immunized and challenged human volunteers to a heterologous strain of P. falciparum sporozoites

To determine protective immunity against a heterologous P. falciparum sporozoites re-challenge after previous CPS immunization and challenge.

Re-exposure of EHMI-8 human volunteers to live malaria sporozoites

Objectives: • Primary objective (parasitological): To explore the longevity of immunity against P. falciparum sporozoite challenge that was induced in the EHMI-8 study. • Secondary objective (immunological): To dissect mechanisms of protection and…

Long-term outcomes of pulmonary function in HIV-infected patients with a history of Pneumocystis jirovecii pneumonia

Assessing the prevalence of pulmonary function testing abnormalities in HIV-infected patients with and without a history of PJP.