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Clinical validation of a dried blood spot (DBS) method for the analysis of immunosuppressive and antifungal drugs in pediatric patients (part of the PROTECT study).

Approved WMORecruitment stopped

PrimairyTo clinically validate a finger prick DBS method compared to conventional venous sampling for the analysis of 5 immunosuppressive and 4 azole antifungal drugs in the pediatric population. Secondairy• Feasibility of the novel finger prick DBS…

Bioavailability of voriconazole in critically ill patients

Approved WMOWill not start

The objective of this study is to obtain the absolute bioavailability of voriconazole in critically ill ICU patients.