Search for a trial

Brain activation in fecal storage, defecation and fecal incontinence: an fMRI study in healthy volunteers, fecal incontinent patients and sacral neuromodulation

The purpose of the present study is the identification of brain areas and patterns involved in the sensory process of fecal urgency, and how these areas and patterns are influenced by sacral neuromodulation. We hypothesize that fecal incontinent…

Role of host cell DNA methylation analysis in predicting non-regression or regression of high-grade anal intraepithelial neoplasia in HIV+ men trial (MARINE)

In this study we clinically validate if host cell DNA methylation markers can predict (non-)regression of HGAIN, thus determining the need of immediate treatment versus active surveillance and the safety of withholding treatment. This could prevent…