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Solace European Confirmatory Trial: An Evaluation of the Solace Bladder Control System in the Treatment of Female Subjects with Stress Urinary Incontinence.

To confirm previous study results using a Solace Balloon and to support future marketing efforts in the European Union and provide data for publications.

Uremic Toxins, Cardiovascular Effects and Physical Activity in Intensive Hemodialysis

The primary objective of this study is to compare vascular biology (vascular markers and endothelial microparticles) and cardiovascular effects (volume status, blood pressure, pulse wave velocity and microcirculation) in conventional hemodialysis (…

The central cause of overactive bladder, a pilot study

The objective of this study is to proof the presence of lesions in the brain of patients with overactive bladder and urge-incontinence (OAB wet) as a central cause of this disorder. This survey is a pilot investigation for a larger study on the…

Clinical parameters and biomarkers in blood and urine as predictors for bacteremia, hospital admission, morbidity and outcome in patients with complicated urinary tract infections.
A study in primary care, the medicine emergency room and ICunit.

Establish relevance of a clinical scoring system, and of established and to be identified biomarkers in blood and urine for clinical course and clinical and microbiological outcome of patients with a complicated urinary tract infection, treated in…

Alpha-1-microglobulin to diagnose acute pyelonephritis

We want to prove wheter the A1M/creatinine ratio in the urine is a good marker to diagnose an APN, or not. The study design has been made of a prospective observational cohort, controlled by a DMSA-scan.Our aim is to use the A1M/creatinine marker in…

Implementation of a clinical decision rule to optimize hospital admission policy of patients with febrile urinary tract infection

To validate a clinical decision rule to guide need for hospitalization in patients presenting with febrile urinary tract infection (FUTI) with the aim to reduce the hospitalization rate without compromising clinical outcome.

Oral Fosfomycin versus Ciprofloxacin for Febrile Urinary Tract Infection in Men: a pilot study

To determine the efficacy of oral fosfomycin in comparison to the standard of care oral ciprofloxacin, in the treatment of FUTI after initial empirical treatment with intravenous antibiotics.To describe the pharmokinetic profile of men treated with…

The influence of sacral neuromodulation on brain areas involved in the sensation of bladder filling in patients with Overactive Bladder (OAB) using fMRI

2.1 Primary Objectives• To identify brain activation evoked by sensation in response to bladder filling in patients with an implanted sacral neurostimulator as a treatment for overactive bladder (OAB), compared to a baseline in OAB patients without…

*The Experience Sampling Method (ESM):
a real-time Patient-Reported Outcome Measure for symptom assessment in patients with overactive bladder syndrome.*

This project will be subdivided into three sections:Part I. Comparison of the ESM vs. SR-BDs and other retrospective questionnaires in the assessment of urological complaints in OAB such as urgency. Part II. Validation of new patient-reported…

The effect of methenamine hippurate to reduce antibiotic prescribing due to new episodes of urinary tract infections (UTI) in elderly women with recurrent UTI- a triple-blinded, randomized placebo-controlled phase IV study

Primary objective: The primary objective of this study is to investigate if taking methenamine hippurate reduce the need for antibiotic usage due to recurrent UTI (measured as the number of courses of antibiotics).Secondary objectives:to investigate…

Urinary tract infections in postmenopausal women revisited

The primary objective is to explore the urine microbiome (urobiome) composition of postmenopausal women with and without RUTI at five scheduled time points during one year of follow-up, as well as before, during, and after UTI episodes when they…

The effect of direct urinary catheter replacement among adults with UTI, systemic manifestations and indwelling catheter in comparison with replacement after two days of antibiotics.

The purpose of this pilot study is to determine the optimal timing to replace a catheter in patients with an indwelling catheter and systematic symptoms of an UTI.