15 results
The main purpose of this study is to find out whether EMDR is a safe and effective treatment to reduce the symptoms of PTSD in people with mild intellectual disability and borderline intellectual functioning. In addition, it is expected to reduce…
The primary objectives of this study are:* To evaluate tracer kinetic models for the purpose of quantifying specific binding of 18F-AV-1451 in cross sectional and longitudinal applications; and* To evaluate simplified methods for quantification of…
The objective for this study is threefold. The first goal is to objectify differences in brain function between patients and normal controls. The second objective is to support preliminary findings that the combination of CBT/PMT is an effective…
Primary Objective: * Is CBM-I successful in changing the cognitive bias in patients with cluster-C personality disorders or personality disorder NOS?Secondary Objective(s): * Will patients following CBM-I show a significant reduction in symptoms and…
Primary objective:To show that concomitant use of telaprevir (1125 mg BID) does not lead to a relevant decrease (> 20%) in the paroxetine parameter AUC0-24h compared to paroxetine alone.Secondary objectives:To determine the ratio of the…
Objectives: To investigate if it is feasible to study giving light therapy to patients with schizophrenia or schizoaffective disorder who are admitted to a clinic. The secondary objectives are to investigate whether light therapy can also help to…
The evaluation of a group therapy for patients with depressive symptoms after stroke - a pilot study
The objective of the study is to investigate the effect of the *Coping with depressive symptoms after stroke* course on depressive symptoms and quality of life in a waiting list controlled study.
Primary Objective: The main aim of this study is to investigate if EMDR diminishes negative associations with fatigue in CFS-patients who follow CBT.Secondary Objective(s): Second, we will investigate if EMDR strengthens the belief of the patient…
Primary research question:- Does treatment with drugs modulating vasoconstriction, i.e. COX-inhibitors (acetaminophen) or calcium-antagonists (nimodipine), improve electrographic postictal phenomena?Secondary research questions:- Does treatment with…
To 1) clinically validate the novel PET-tracer [18F]AV1451 for tau pathology as a diagnostic and prognostic marker in tauopathies, 2) to examine the (change in) (regional) binding of [18F]AV1451 across tauopathies, and the relationships between (…
The aim of this study is to investigate the effectiveness of a more intensive and longer protocol group ST (12-15 months) combined with individual sessions in older adults (aged 60 and older) diagnosed with Cluster B and/or C PDs.
The primary objective of this study is to evaluate the efficacy of psilocybin (25 mg or 10 mg) compared to 1 mg, administered under supportive conditions to adult participants with TRD, in improving depressive symptoms, as assessed by the change in…
To evaluate the acceptability and effectiveness of a deepfake victim-perpetrator confrontation in young adults with sexual violence-related PTSD.
The aim of this this study, is to test whether EMDR therapy, relative to a baseline phase, results in: 1) less social anxiety symptoms, and 2) less social avoidance symptoms
The goal of the study is to examine whether optimal exposure is more effective than CBT as usual in youth with anxiety disorders. The secondary objective is to investigate whether decreases in harm expectancies are predictive of treatment outcome,…