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A Study of Respiratory Muscle Strength, including Effort-Independent Measures, in Subjects with Late-Onset Pompe Disease

The primary objective of this study is to compare respiratory muscle strength values obtained using volitional techniques with values obtained using non-volitional techniques. The secondary objective is to compare the change for these two sets of…

Long-Term Multi-center Evaluation of E-Poly* and Regenerex* Cementless Acetabular Components: Clinical and Radiographic Outcomes

The purposes of this long-term mutli-center study are: - To compare the long-term (10-year) radiographic and clinical outcomes of new E-Poly* liner in primary total hip arthroplasty with the conventional ArcomXL® polyethylene liner.- To compare the…

Pharmacokinetic Profile of Ropivacaïne after Periarticular Local Infiltration Analgesia for Primary Total Knee Arthroplasty

The primary objective of this study is to describe a pharmacokinetic profile of bound and unbound plasma concentrations of ropivacaïne, when used in the LIA technique for the knee. Especially describing the Cmax and Tmax gives arguments for dosage…

Long-Term Functional Results of Ewing Tumor Treatment

The primary objective is to measure the real-world daily activity in a representative cohort of 1100 longterm survivors after Ewing tumor treatment using portable devices, and to describe the functional outcome and health-related quality of life…

Relation among shoulder kinematics and kinetics during thoracohumeral elevations, performance of standardized ADL tasks, rehabilitation exercises, and clinical outcome measures in patients with a primary placed total shoulder prosthesis

The purpose of this study is to evaluate the relation among shoulder kinematics during thoracohumeral, glenohumeral and scapulairthoracic elevations, performance of standardized ADL, Activitities od Daly Life, tasks and clinical outcome measures of…

Implementation of a strategy of osteoporosis screening in patients over 50 years of age with a first fracture, with intensive treatment and follow-up by a nurse-practitioner to prevent recurrent fractures in those patients with diagnosed osteoporosis

Is it possible to improve routine detection and treatment of osteoporosis after an initial fracture?I) is it possible to increase the proportion of patients adequately screened and categorized as to the presence of osteoporosis from current practice…

TIP-glucocorticoids research UMCU rheumatology; Cardiovascular risk factors and insulin resistency in reumatoid arthritis patients with and without glucocorticoids.

- To systematically determine metabolic adverse affects of RA patients, who (chronically) use GCs in order to reduce disease activity, compared to RA patients who don*t use GCs.- To study the relation between disease activity, treatment, and…

Comparing the migration and inducible displacement through RSA of the cementless ATTUNETM Rotating Platform and the cementless LCS Rotating Platform Knee system; A Clinical Randomized Controlled RSA follow-up study*

The primary aim of this study is to accurately compare the mid and long-term migration of two uncemented total knee prostheses. The secondary objectives of this study are to evaluate whether inducible displacement can be used as a parameter to…

*A prospective randomized multicenter study to demonstrate the superiority of the Barricaid® to discectomy for primary lumbar disc herniation*: Extended Follow-Up of the Barricaid® Annular Closure Device (ACD) Randomized Control Trial (RCT) Postmarket Cohort for Lumbar Disc Herniation and Interaction with Other Risk Factors

The purpose of this post-approval protocol amendment is to extend the follow-up of subjects who were originally enrolled in theRCT, EUBARD-CP_001 protocol. This study extension will examine the long-term survivorship of the Barricaid® ACD when…