11 results
Incidence of type 2 diabetes mellitus and cardiovascular disease in familial combined hyperlipidemia
To determine: 1) the incidence of type 2 diabetes mellitus in FCHL patients, normolipidemic relatives and their spouses2) the incidence of cardiovascular disease in FCHL patients, normolipidemic relatives and their spouses3) the prevalence of CESD…
To determine whether a difference in resilience of inflammatory tone between healthy and prediabetic males can be identified with whole blood ex vivo LPS stimulation.
We hypothesize that impaired insulin uptake into skeletal muscle interstitium (thus decreased transendothelial transport of insulin) is impaired in patients with type 2 diabetes mellitus. This hypothesis will be addressed in the present study.
a) To investigate the differences in adipokines and inflammatory markers between obese and normal weight children; b) to study these differences over age, and c) to correlate adipokine/inflammatory marker profiles to clinical parameters for obesity…
Primary objective:To compare the mean absolute glucose change in postoperative older patients with and without a delirium.Secondary objectives:1. To compare the mean glucose concentration and glucose variability in postoperative older patients with…
the first objective of this study is to quantify the impact of chronic Q-fever or QFS on work status and psychosocial functioning. Secondly, we will identify factors that are associated with these limitations, to determine which subgroups of…
Primary Aim: We aim to determine markers for NOX2-mediated insulin-independent glucose uptake signalling pathways, mitochondrial function, myokine secretion both at rest and after a bout of acute exercise in individuals with T1DM and healthy…
The primary objective of this study is to determine the variation in postprandial glucose responses to the same meals/food products and how this relates to the variation in postprandial glucose responses over a 9-week fully controlled dietary…
To perform a patient satisfaction study on the Equil patch pump in T1DM patients that currently already use CSII in combination with CGM or Flash glucose monitoring.
Primary objective: Develop a completely novel and non-invasive method to map body metabolism in humans based on DMI on a 7T MRI scanner.Secondary objectives: To demonstrate proof of concept by measuring (1) hepatic glucose metabolism and (2) de…
The main objective of this study is to determine whether prediabetic individuals and those already diagnosed with type 2 diabetes show differences in sweet taste perception and whether this difference is related to their oral and/or gut microbiota…