12 results
Primary objective of this study is to assess the reliability and validity of the neuromuscular parameters of ankle joint impedance estimated by nonlinear SIPE technology in children with CP compared to current clinical manual tests and gait analysis…
Primary Objective: to derive iPSCs from patients with a variety of diseases caused by genetic mutations or genetic predisposition to disease or of unknown origin. The cells will be propagated and differentiated into a variety of somatic cell types…
1. Discribe the normal development of mastication in healthy children aged between 6 and 48 months by using the Mastication Observation and Evaluation (MOE). Which oral motor behaviours occurs?2. Determine the differences in mastication between…
Using a variety of methods, we try to determine the dynamics of the chewing movements in typically developing children and children with CP. The methods are, in some degree, complementary to each other. Given the limitations of the methods we need…
To establish benchmark values in healthy control fetuses, to compare these with our cohort of fetuses with severe CHD.
The primary objective of this study is to determine whether 3D kinematics, kinetics and spatiotemporal parameters during walking on the V-Gait system are comparable to overground walking in children with cerebral palsy and in healthy children…
To optimize the 3D ultrasound reconstruction and dynamometer as a clinical tool for measurement of morphological and mechanical muscle properties, and to compare the m .gastrocnemius medialis of healthy children to the m .gastrocnemius medialis of…
1. The development of a standardized screeningsinstrument to evaluate the language comprehension of severly handicapped children with movement disorders and who cannot speak, as a result of white matter damage.2.To evaluate the difference between…
To determine to what extent dynamic spasticity can be recognized and quantified in the gait pattern of children with spastic CP and to develop a meaningful and (clinically) applicable measure of dynamic spasticity
The main goal of the VUmc part of the study is to acquire sets of data related to Neurological and Neuromuscular Diseases; in order to build a paediatric digital repository and to develop biophysical modelling and probabilistic modelling.
To improve prediction of neurological and functional outcome at school age in infants at high risk of cerebral palsy.
The primary objective of the study is to develop new sensitive and quantitative outcome measures for clinical trials in ALD. The secondary objective is to identify biomarkers to stratify patients based on disease progression rate.