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A phase IIb, Double Blind, Randomized, placebo- controlled, Double-Dummy, Dose Rangining Study To Evaluate the Clinical Efficacy and Safety of Induction and Maintenance therapy with BMS- 945429 in subjects with Moderate to Severe Crohn's Disease.

Objectives1.3.1 Primary ObjectiveCompare the efficacy of BMS-945429 versus placebo for induction of clinical remission (defined by an absolute Crohn*s Disease Activity Index [CDAI] score < 150) at Week 8 (IP-57).1.3.2 Secondary Objectives•…

Misophonia: an imaging study on the neurobiology and the efficacy of cognitive behavioural therapy

The objective for this study is threefold. The first goal is to objectify differences in brain function between patients and normal controls. The second objective is to support preliminary findings that the combination of CBT/PMT is an effective…

A multicenter, randomized, partially-blinded, Phase IIb dose-finding study on ovarian function, vaginal bleeding pattern, and pharmacokinetics associated with the use of combined vaginal rings releasing 17*-estradiol plus three different doses of either nomegestrol acetate or etonogestrel in healthy women aged 18-35 years;

The main objective of the trial is to identify at least one NGR that will demonstrate all of the following:1. Inhibition of ovulation2. Cycle control that is non-inferior to NuvaRing®, as judged by the incidence ofBTB-S during Treatment Cycle 3. The…

Using the Vestibular Labyrinthine Substitution system in daily life

To objectify the effect of the VLS-system during daily use regarding postural stability and quality of life.