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The effect of fibrate therapy in two patients with neutral lipid storage disease with myopathy (NLSDM).

We would like to evaluate the beneficial effects of fibrate treatment on muscle mitochondrial and cardiac function in patients with NLSDM.

A prospective open-label study to investigate the effects of switching to a darunavir based regimen on low level viremia, immune activation and neurocognitive performance in patients on antiviral therapy.

To suppress low-level viremia to a level below 50cp/mL in patients using cART by switching their current non-nucleoside reverse transcriptase inhibitor (NNRTI) or PI to DRV boosted with ritonavir (RTV) (DRV/r). Secondary objectives are to reduce the…

Inhibition of platelet activation by clopidogrel in type II diabetes mellitus patients

The objective of the study is to gain new insights in the causes of a higher clopidogrel resistence in type II diabetes mellitus patients

The Effect of Oral Contraceptive Onset on Emotion Regulation in Adolescence

The primary objective is to research whether the oral contraceptive pill in adolescents has a negative effect on emotion regulation in the form of fear acquisition and extinction. The secondary objective is to research whether a disruptive effect of…

The noradrenergic basis of Parkinson*s tremor: a systems-level fMRI approach

I will test the hypothesis that the noradrenergic system amplifies tremulous activity in the cerebello-thalamo-cortical circuit. More specifically, I will test how this modulation takes place (i.e. through which brain regions and connections).