14 results
To study the antibody response as a disease modifying factor in the context of COVID-19, we will compare the anti-CoV antibody composition, quality and interaction with immune receptors.
To investigate the relationship between body composition and parenteral nutrition in children with intestinal failure at 6 months corrected age. The ultimate goil of this study is to optimize the treatment of children with intestinal failure by…
Primary objective: To identify rare, high impact genetic variants in immunological genes and pathways in children with a history of MIS-C or pediatric post-COVID condition. Secondary objectives: To analyze the clinical characteristics and long-term…
The main aim is to study early neurocognitive functioning and development in very young children with SCD. The secondary aims are to identify determinants (risk and protective factors) and biomarkers of early neurocognitive deficits in SCD and to…
To validate biomarkers that are associated with severe RSV infection and respiratory sequelae.
Primary Objectives: 1. To assess the metabolic profile of patients with Dravet syndrome and identify metabolic variations that contribute to the pathophysiology of seizures and developmental delaySecondary Objectives:2. To assess the association…
The main objective of this proposal is to establish ex-vivo models of bronchial epithelial cells from children. Use of (1) epithelial organoid cultures derived from bronchial or nasal epithelial cells; and of (2) bronchial brushings; (3) nasal…
In 2004, a multidisciplinary team of clinicians and researchers in the UZ Leuven hospital started to collaborate on the rare problem of cancer during pregnancy. The collaboration between gynaecologists, pediatricians, hematologists, farmacologists,…
Primary objectives: The first aim is to examine the role of microtubule network in electrical conduction, protein localization and function in induced cardiomyocytes from pediatric BrS patients, life threatening ventricular arrhythmia patients and…
Investigating red blood cell deformability changes, during treatment, measured with hyperoxia-hypoxia ektacytometry in sickle cell anemia patients, patients with HbSC disease and patients with HbS-beta-thalassemia.
The aim of the DONOR study is to define if OD pregnancies, specifically those with immunogenetic differences between mother and child, are associated with abnormal placentation and vasculogenesis, resulting in distinct maternal immunomodulation and…
The PROUD-kids 2.0 study aims to find parameters to identify and distinguish between the different subtypes of ADS. Also finding predictive factors for disease course and disease severity. Genetic and environmental factors will be investigated to…
This study intends to investigate the diagnostic potential of the Capilia mac antibody Elisa test in children with a clinical suspicion of NTM cervicofacial lymphadenitis.Moreover, this study aims at investigating whether NTM possibly access the…
Primary:- Investigate the feasibility of examining fetal and neonatal brain developmental trajectories in the fetus and neonate with at least one parent with SMI in the mood-psychosis spectrum (vs. parents without SMI) using MRI.- Acquire…