20 results
Various brain areas play a crucial role in both pain and cognition, supporting the existence of a close relationship between pain and cognition. Consequently, it is important to examine whether pain experience changes at the moment the patient shows…
In humans with SCI, we propose to use functional magnetic resonance imaging (fMRI) to: 1) examine the cortical areas that are activated during voluntary contractions, and 2) evaluate how cortical activation patterns change as a muscle is fatigued.…
The aim of this experimental study is to find out whether children and young adults with the DS have an altered pain sensitivity in comparison with children and young adults without cognitive impairement.
To investigate whether patients with schizophrenia show reliable and consistent brain activations as measured with fMRI to two different stimulation paradigms and wether they differ in terms of the patterns or the intensity of activation as compared…
1. To determine the prevalence of gastric fundic gland polyps in patients undergoing routine upper gastrointestinal endoscopy2. To determine the prevalence of dysplasia in these gastric fundic gland polyps3. To determine the prevalence of gastritis…
In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…
HypothesisSexual function in female systemic sclerosis patients is impaired as a result of fibrosis of the genital tract, fatigue, chronic pain, Raynaud*s phenomenon and contractures. AimThe aim of the study is to investigate sexual function and its…
The primary objective of this study is to identify the brain changes following peripheral nerve injury and establishing their functional role in recovery. The secondary objective is to evaluate new fMRI methodology in a patient population.
The present study aims at exploring a visuo-tactile mirroring mechanism in patients with autism. Furthermore, the relationship between neural tactile simulation processes, empathic abilities, and symptom severity in the social domain will be…
Our primary objectives are to evaluate - if endogenous EPO, EPC levels and EPC function are different in patients with stable and unstable CAD, compared to age and sex matched controls;- if a correlation exists between endogenous EPO and EPC levels…
In our own recent studies we found indications of the existence of particular executive functioning deficits as well as memory impairments following different regimens of cytotoxic agents. Together with the indication from our animal study of a…
To study the spread of STI among heterosexual males and females (heterosexuals) in Amsterdam in order to provide information for building evidence-based prevention strategies and to evaluate existing control programs. Three substudies are part of…
The overall aim of this study is to examine, in adult female CCS in the Netherlands, the effects of treatment in general, and the effects of different types of treatment, doses of drugs, radiation sites and doses, and age at time of treatment, on: 1…
The aim of this study is to investigate the neural correlates of different types of emotion regulation and emotional processing underlying social cognition.
1) to investigate the occurrence and severity of muscle loss in patients with AS,2) to explore determinants of muscle loss,
To evaluate test - retest replicability of, in particular, the frontostriatal network, and the implications thereof on future studies. We will also aim to implement ways to increase the replicability of functional MRI results.
The aim of the present study is to evaluate the long-term pulmonary sequelae, exercise endurance and perception of exercise endurance in adult CDH patients in a cohort that has been studied earlier at a median age of 11.7 years. Lung function…
1.To investigate the relationship between amblyopia and the development of the neurosensory retina:Measurements: Central / foveal retinal thickness RNFL Inner retinal layer thickness thru segmentation algorithms 2.To investigate the differences in…
The main objective is to understand the role of the noradrenergic system in human cognition by testing specific hypotheses about task performance in D*H patients. A secondary objective is to understand whether and how cognitive function is…
Main objectives: To obtain true population-based prevalence and incidence figures, as well as insight in the natural history of PSC and PBC in The Netherlands.Secondary objectives: to determine risk factors correlated with PSC and PBC respectively,…