20 results
This study investigates the impact of a goal directed nutritional support protocol on sarcopenia in oncological patients undergoing an esophagectomy and secondary the incidence of anastomotic leakage and pneumonia, surgical infection and lenght of…
The primary objective of the study is to examine muscle atrophy in fetuses with single or bilateral IPEV, in comparison to a normal population by measuring the circumference of the upper and lower legs by ultrasound examination. The length of the…
The objective of this study is to determine whether contralesional cTBS treatment modulates the interhemispheric imbalance in excitability or local or transcallosal inhibitory processes in the motor network of a population of stroke patients…
To evaluate tailoring components in a web application for THA patients and to refine guidelines for tailored web applications for patients.Secondary objectives:- To assess how and how often THA patients use a prototype of the tailored web…
HV cohort 1Primary Objectives* To characterize the local tolerability of topical bimiralisib after 21 days* To characterize the systemic PK of topical bimiralisib after 21 daysSecondary Objective* To characterize the safety of topical bimiralisib…
To assess the effectivity and feasibility of HCV RNA self-testing in reducing the time to diagnosis of HCV re-infection in MSM previously cured of an HCV infection, compared to the current diagnostic standard of care. To evaluate whether the uptake…
Primary objectives* To correlate social, physical, and biometric activity of FSHD patients with the FSHD Clinical Score (Lamperti) and the Timed Up-and-Go Test.* To evaluate the feasibility and subjective burden of remote monitoring in FSHD patients…
Primary objective: The primary objective of this study is to assess the effectiveness and cost-effectiveness of the Transmural Trauma Care Model (TTCM) as compared to usual care.The research question addressed is:Is the Transmural Trauma Care Model…
The objectives of this study are to:• Assess safety and tolerability of imlifidase in combination with standard IVIg treatment in GBS subjects• Evaluate pharmacokinetics of imlifidase• Evaluate pharmacodynamics profile of imlifidase• Evaluate…
Primary Objective: This study aims to investigate the positive, negative or lack of effect that CBTi has on insomnia in tinnitus patients.Secondary Objective(s): Investigate the positive, negative or lack of effect that CBTi has on tinnitus…
Primary objective:- Determine whether PCT, measured in cord blood, and the blood of the neonate, is suitable to determine the presence or absence of neonatal infection.Secondary objective:- To investigate whether PCT is a suitable parameter to…
Our goal is to build up a deep phenotyped HFpEF cohort, to be able to select the right patients for different HFpEF studies with the final goal of improving the understanding of the pathophysiology of HFpEF. The HFpEF cohort will allow us to…
Primary objectives1. To evaluate the pharmacokinetic (PK) profile of the parent compound (anethole trithione, ATT) and its main metabolite (5-[4-hydroxyphenyl]-3H-1,2-dithiole-3-thione, ATX ) following administration of a range of doses of i.v.…
Primary objectiveTo evaluate current clinical practice and develop a population based Campath® (Alemtuzumab) pharmacokinetics model for predicting total Alemtuzumab exposure after i.v. administration before allogeneic stem cell transplantation in…
To compare implant loss between single-stage BAHI surgery (test group) and two-stage BAHI surgery (control group) in children. Furthermore, to compare soft tissue status, time to loading and duration of surgery between groups.
To determine the influence of concomitant administration of Lonsurf with metformin and cimetidine on Lonsurf and metformin exposure.
The aim of this pilot study, the *Ventilation, inflammation, perfusion and structure imaging in Neonatal Lung patients* (VINyL) study, is to develop a safe and fast MRI protocol for neonatal airway, lung and cardiac imaging in neonatal lung patients…
The primary objective of the study is to explore the role of inflammation in the anterior chamber on endothelial cell loss in patients implanted with iris-fixated pIOLs. The secondary objective is to identify whether there is a correlation between…
Main objective is to identify ion-channel dysfunction in motor nerve cells of individual ALS patients, that contributes to their death, by assessing the association between ion-channel function tests in lower motor neurons and survival of patients…
To assess whether HBOT reduces pain, and improves physical functioning and QoL in breast cancer patients with late radiation toxicity.