79 results
(I) Investigating the role of the cholinergic system and CBGTC-loop in the pathophysiology of CD, related to both motor and NMS; (II) Finding a biomarker for DBS efficacy in CD, including motor and NMS.
Primary Objective:Delineate the differences in cellular composition and function at the maternal-fetal interface in patients with SLE compared to healthy women Secondary Objectives:- Establish a novel in-vitro model to study cell-cell interaction at…
By means of this study we want to find out whether there are certain characteristics that can influence or predict the course of Crohn's disease. We want to do this by collecting data on diet, inflammation levels in the blood, complaints and…
The primary aim is to determine whether the relative aerobic load of walking is a determinant of the amount of walking in daily life in people with a chronic spinal cord injury with a walking function. Secondary goals are to gain insight into other…
To study the neuroplasticity of the brain due to facial synkinesis by assessing the somatotopy of the face on several cortexes of interest (primary and secondary somatosensory cortexes, the primary motor cortex, the supplementary motor cortex, the…
Our objective is to safely increase the visit interval to 6 months in JIA patients with stable disease. The skipped 3-month visit isreplaced by a self-evaluation via e-mail by EQ-5D-5L-Y and JAMAR questionnaires that will be send via Castor EDC.…
This study has been transitioned to CTIS with ID 2024-517258-85-00 check the CTIS register for the current data. The primary objective of this study is to determine the feasibility and safety of quantitative fluorescence endoscopy using the…
To investigate te efficacy and the toxicity of protone radiation of thymomas and thymic carcinomas.
1. to test differences in movement patterns during a standardized lifting task and gait between patients with chronic low back pain with high central sensitization (CS+), low back pain with low/moderate central sensitization (CS-) and healthy…
Primary objective: Our primary objective is to investigate whether niagen normalizes blood-based energy metabolites, mitochondrial levels and proteostasis levels. Secondary objective: To examine whether niagen reduces AF burden in patients with…
This study has been transitioned to CTIS with ID 2024-512244-36-00 check the CTIS register for the current data. The objectives of this are to establish the safety, tolerability, and efficacy of VRDN-001, and the pharmacokinetic (PK) and…
The aim of the study is to determine whether children who have been admitted to the ICU for an RSV infection in their first year of life and now are at school age:1. have more respiratory complaints than controls (based on a short questionnaire…
Beyond mapping the pregnancy-related neural plasticity in structure and function, this project is designed to reveal functional and behavioral implications of the transformations impacting a woman*s brain across this major transitional stage. The…
The main objectives of this study is to analyze differences in the gut and vaginal microbiome between healthy and PCOS women and investigate whether these differences correlate with PCOS characteristics. In addition, we want to look at a possible…
Primary Objectives: 1. To investigate the nature and extent of persistent fatigue and cognitive complaints 2. To investigate the impact of persistent complaints on health-related quality of life and health care consumption3. To identify risk factors…
With this study, we aim to gain insight in the influence of dietary oxalate on urinary oxalate levels by quantification of the intestinal oxalate absorption in patients with recurrent idiopathic calcium oxalate stones, primary hyperoxaluria, and…
To evaluate the effect of FICare in SFR on cognitive development at 5.5 years of age as measured by the WPPSI-IV in preterm infants hospitalised in a level-2 Neonatal Ward as compared to SNC in OBU To evaluate the effect of FICare in SFR on parental…
The primary objective of the second part of the study, which is the focus of this application, is to perform a comparative analysis of the cognitive profile and MRI outcomes of DMD/BMD patients.
To assess the efficacy of treatment with Endocalyx for chronic heart failure.
This project aims to investigate the additive value of an optimism intervention to an existing rehabilitation protocol for pain patients. It is expected that including an optimism module in an exposure in vivo treatment or a graded activity…