19 results
The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI and (2) to evaluate whether training viewing strategies results in more efficient…
To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning, academic achievement, physical morbidities and growth of MLPTI at the age of 9 years and correlate this with BSID-III-NL…
The aim of this study is to improve the conservative management of OCLs of the talus in the skeletally immature due to the comparison of two different conservative strategies. An optimal conservative treatment can result in a better quality of life…
Primary objective:-To confirm that the Event-Free Survival (EFS) in patients >= 3 years of age with WHO grade IV/CNS WHO grade 4 and WHO grade III/CNS WHOgrade 3 diffuse high grade gliomas as well as diffuse high grade gliomas without a…
The objectives of the proposed research are: (1) to characterize the neural correlates of verbal learning abilities (both for nouns and verbs) in typically developing (TD) children compared to children with DLD, aged 8-12 years old. (2) to…
The aim of this study is to investigate the effectiveness of MST-ID for adolescents with severe behavioural problems from families with an intellectual disability (ID), compared to standard MST. It is hypothesised that MST-ID (n = 150 families) is…
The main aim is to study early neurocognitive functioning and development in very young children with SCD. The secondary aims are to identify determinants (risk and protective factors) and biomarkers of early neurocognitive deficits in SCD and to…
To identify genetic variants for the development and progression of keratoconus using Whole Exome Sequencing and Whole Genome Sequencing approaches on keratoconus families with index patients originating from the Rotterdam Eye Hospital and Erasmus…
To determine the long-term outcome after necrotizing enterocolitis during neonatal life, regarding (pain) sensitivity, sensory processing, behaviour, executive function, scar satisfaction (in surgically treated NEC patients), and (health-related)…
This study has been transitioned to CTIS with ID 2024-510919-29-00 check the CTIS register for the current data. OBJECTIVES - Phase 2 (not to be conducted in NL):Phase 2 Primary Objective:- Identify a setrusumab dosing strategy in subjects with OI…
The primary objective of the cohort study is to test the effectiveness of a complex intervention of paediatric sleep problems on a 24-hour sleep duration (day- and nighttime) of children aged 6-36 months of age with sleep onset and/ or sleep…
The aim of this study is to identify whether the availability of a PSD for military veterans with PTSD coincides with clinically significant changes in wellbeing, behaviour and functioning in veterans and their families compared to veterans with…
The aim of our study is to investigate whether a tailored nutritional care follow-up program in children who are being discharged from the hospital with nutritional support improves nutritional intake and status as well as feeding behaviour and…
This study has been transitioned to CTIS with ID 2024-515025-28-00 check the CTIS register for the current data. To determine the efficacy of treatment with mitapivat compared with placebo, as assessed by the increase in Hb concentrations in…
Primary Objective: - To assess the effect of MMR-0 vaccination on the humoral immunity against measles 2 years (+/- 2 months) after MMR-2 vaccination.Secondary Objective(s): - Determine the effect of MMR-0 vaccination on the humoral immunity against…
The first aim is to determine an objective acoustic measure to define SMS by comparing acoustic features of probe words to a perceptual score of speech motor movement characteristics and stuttering frequency judged by the expert (i.e., the current…
Objective: The main objective is to evaluate the monocyte phenotype of children with FH compared to normocholesterolemic controls and to explore the effect of statin treatment.
The main objective of this study is to investigate whether there are differences in the way factors such as learning progress (LP) maximization and prediction error (PE) minimization drive the exploratory behavior of children with autism compared to…
The main objective of this proposal is to establish ex-vivo models of bronchial epithelial cells from children. Use of (1) epithelial organoid cultures derived from bronchial or nasal epithelial cells; and of (2) bronchial brushings; (3) nasal…