1386 results
1. Is there a difference between the level of activities and participation among adolescents with chronic musculoskeletal pain as compared with the activity and participation level of adolescents not suffering from chronic pain?2. What is the impact…
To assess whether close rectal restorative proctocolectomy with IPAA has a better outcome regarding postoperative vaginal vasocongestion and reported psychological and sexual functioning then IPAA by TME restorative proctocolectomy.
The primary goal of the proposed study is to investigate the dopamine D2 receptor binding potential in patients with body dysmorphic disorder (BDD) and patients with trichotillomania (TTM) in comparison to healthy subjects. As BDD and TTM are OC…
With this project we aim to clarify the differences in airway pathophysiology between asthmatics and healthy controls that underlie the prolonged survival of virus and the exaggerated inflammation in virus-induced exacerbations of asthma. We will…
In our opinion, CTCs could serve as a pharmacodynamic marker to monitor anti-cancer therapy in clinical trials. Encouraging results, that show that CTCs have pharmacodynamic properties, were recently found in a prospective trial in which CTC number…
The aim of this study is to improve insight in potentially genetic factors contributing to the development of pyloric stenosis.We aim to investigate the association of the COL3A1 gene and pyloric stenosis because of concrete signs in the existing…
Primary objective:Study A: Development, validation and reproducibility of a method to assess arm activity.Study B: Investigate the association between muscle effort and arm use during a series of daily activities in COPD patients and healthy age…
To gain more insight into the pathogenetic processes involved in SS by analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and non-inflammatory…
Main objectives: Establishing the effect of BF as predisposing factor for the development of VGE and hence DCS by using subjects with a restricted range in age and VO2max. Establishing the effect of TC/HDL ratio and FFA as predisposing factors for…
Hypothetically, in patients with PBC or PSC the FGF-19 production or -response could be altered. The goal of this research is to study the FGF19 production after a standardized oral fat challenge and the effect of this FGF19 production on bile acid…
In this study, we will assess whether healthy and hypertensive subjects with high-normal serum CK display greater salt retention and vascular contractility, compared to those with low-normal serum CK.
To obtain more information on peripheral muscle properties that can account for the reduced exercise capacity in patients with PPS compared to healthy subjects, and to develop an alternative method for determining aerobic exercise capacity in…
To determine whether different MR-based imaging techniques and FibroScan can be used for the purpose of identifying and monitoring Gaucher Disease patients at high risk of developing disease related liver complications.
The study has three main objectives:a) to investigate whether autistics can achieve normalized levels of language processing when receiving explicit attentional instructions. b) to study if (and if yes, how) an instructed attentional change towards…
To demonstrate completeness of occlusion of the segmental portal branches after unilateral PVE by intraoperative portography. A secondary aim is to assess the perfusion of the liver after PVE on microvascular level by O2C and ICG clearance; and to…
Assessment of triglyceride clearance in a FH population with variations in heparan sulfate biosynthesis.
Primary objective: To investigate whether urine prothrombin fragments are increased in individuals suffering from VTE (i.e. PE or DVT) or a myocardial infarction compared to healthy matched controls.Secondary objective: to investigate whether…
This single-center investigation will assess the prevalence of psoriasis in a population of patients with hepatitis C and compare the prevalence in those patients receiving pegylated interferon-* therapy to those not receiving pegylated interferon…
The main objective of the study was to prove the effectiveness of cryoablation in palliating pain and correlate the patients with a matched group of the Dutch bone metastasis study. The secondary objectives are to determine the accuracy of cryoprobe…
The aim of this study is to investigate which (combination of) laboratory situations require the full benefit of binaural hearing.